| William Matthews | |
| Position: | Pitcher |
| Bats: | Unknown |
| Throws: | Right |
| Birth Date: | January 5, 1877 |
| Birth Place: | Mahanoy City, Pennsylvania |
| Death Place: | Mount Carbon, Pennsylvania |
| Debutleague: | MLB |
| Debutdate: | August 28 |
| Debutyear: | 1909 |
| Debutteam: | Boston Red Sox |
| Finalleague: | MLB |
| Finaldate: | September 23 |
| Finalyear: | 1909 |
| Finalteam: | Boston Red Sox |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 0-0 |
| Stat2label: | Strikeouts |
| Stat2value: | 6 |
| Stat3label: | Earned run average |
| Stat3value: | 3.24 |
| Teams: |
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William Calvin Matthews (January 5, 1877 – January 23, 1946) was a right-handed pitcher in Major League Baseball who played briefly for the Boston Red Sox during the 1909 season. He was born in Mahanoy City, Pennsylvania.
Matthews posted a 3.24 ERA in five appearances, including one start, six strikeout, 10 walks, 16 hits allowed, and 16.2 innings of work. He did not have a decision.
Matthews died in Mount Carbon, Pennsylvania, at age 68.