| William Loftus | |
| Birth Date: | 6 March 1975 |
| Birth Place: | Vancouver, British Columbia |
| Team: | Retired |
| Status: | Retired |
| Import: | no |
| Position1: | Safety |
| Height Ft: | 6 |
| Height In: | 2 |
| Weight Lb: | 195 |
| Cis: | Manitoba |
| Cfldraftedyear: | 1998 |
| Cfldraftedround: | 3 |
| Cfldraftedpick: | 18 |
| Cfldraftedteam: | Montreal Alouettes |
| Playing Years1: | – |
| Playing Team1: | Montreal Alouettes |
| Playing Years2: | – |
| Playing Team2: | Edmonton Eskimos |
| Cfl: | 67 |
William Loftus (born March 6, 1975, in Vancouver, British Columbia) is a retired Canadian Football League Safety who played 11 seasons in the CFL with the Edmonton Eskimos and Montreal Alouettes. He was a two-time Grey Cup champion, having won in 2002 with the Alouettes and in 2005 with the Eskimos.