| William I | |
| Landgrave of Lower Hesse | |
| Spouse: | Anna of Brunswick-Wolfenbüttel |
| Issue: | Mathilda Mathilda Anna Katherine Elisabeth |
| House: | House of Hesse |
| Father: | Louis II, Landgrave of Lower Hesse |
| Mother: | Mechthild of Württemberg-Urach |
| Birth Date: | 4 July 1466 |
| Death Date: | 8 February 1515 |
| Death Place: | Kassel |
William I of Hesse (German: Wilhelm) (4 July 1466 – 8 February 1515) was the Landgrave of Hesse (Lower Hesse) from 1471 to 1493.
His parents were Louis the Frank (1438–1471) and Mechthild, daughter of Count Louis I of Württemberg. On 17 February 1488 in Münden, he married Anna of Brunswick-Wolfenbüttel c. 1460 - Worms 16 May 1520], daughter of William IV, Duke of Brunswick-Wolfenbüttel and Elisabeth, Countess of Stolberg, with whom he had five daughters:[1] [2]
After a pilgrimage to the Holy Land in 1491 where he was dubbed a Knight of the Holy Sepulchre, he probably contracted syphilis. He abdicated in favor of his brother William II on 3 June 1493, and spent the rest of his life in Spangenberg.