| William Frederick Holmes House | |
| Coordinates: | 31.2417°N -90.455°W |
| Built: | 1894 |
| Added: | March 22, 2004 |
| Area: | less than one acre |
| Refnum: | 04000216 |
The William Frederick Holmes House, also known as Theosa, is a Queen Anne-style house in McComb, Mississippi, listed on the U.S. National Register of Historic Places in 2004. It was called "one of the largest and most prominent examples of Victorian Queen Anne residential architecture in McComb" and "one of several noteworthy examples in Pike County".[1]