| William Clarke | |
| Residence: | Jersey City, New Jersey |
| Office: | Mayor of Jersey City |
| Order: | 17th |
| Term Start: | April 11, 1869 |
| Term End: | May 1, 1870 |
| Predecessor: | Charles H. O'Neill |
| Successor: | Charles H. O'Neill |
William Clarke was an American politician. He was the seventeenth Mayor of Jersey City, New Jersey. He succeeded Charles H. O'Neill. Clarke served from April, 1869 to May 1, 1870. He was succeeded by Charles H. O'Neill.