Bill Earnshaw Explained

Bill Earnshaw
Birth Name:William Charles Earnshaw
Education:Lenox School for Boys
Alma Mater:Colby College (BS), Massachusetts Institute of Technology (PhD)
Thesis Title:The Structure of Bacteriophage p22 and its Assembly Intermediates
Thesis Url:http://search.proquest.com/docview/302867678
Thesis Year:1977
Awards:EMBO Member (1999)

William Charles Earnshaw [1] is Professor of Chromosome Dynamics at the University of Edinburgh,[2] [3] [4] [5] where he has been a Wellcome Trust Principal Research Fellow since 1996.[6] [7]

Education

Earnshaw was educated at Lenox School for Boys, Colby College and Massachusetts Institute of Technology (MIT) where he was awarded a PhD in 1977 for research on Enterobacteria phage P22 supervised by Jonathan King.[8] [9] [10] [11] [12]

Career and research

Earnshaw completed postdoctoral research at the University of Cambridge with Aaron Klug and Ron Laskey[13] [14] and at the University of Geneva with Ulrich Laemmli.[15] [16] Following this, he moved to the Johns Hopkins School of Medicine, working in Tom Pollard's[17] department of cell biology for 13 years.[6] His former doctoral students include Jan Bergmann,[18] Anca Petruti-Mot,[19] Susana Ribeiro,[20] Laura Wood,[21] Zhenjie Xu,[22] and Nikolaj Zuleger.[23]

Awards and honours

Earnshaw was elected a Fellow of the Royal Society (FRS) in 2013.[24] His certificate of election reads:

Earnshaw is also an elected Fellow of the Royal Society of Edinburgh (FRSE), the Academy of Medical Sciences (FMedSci) and a member of the European Molecular Biology Organization (EMBO).[25]

Notes and References

  1. Web site: Professor William Earnshaw FMedSci FRS . The Royal Society . 2015-06-10 . https://web.archive.org/web/20150610103337/https://royalsociety.org/people/fellowship/2013/william-earnshaw/ . London.
  2. Web site: https://web.archive.org/web/20150610112308/http://www.research.ed.ac.uk/portal/en/persons/bill-earnshaw(61e8a9b5-f04c-40e4-bb6b-4ad305adb5ff).html. 2015-06-10. Prof Bill Earnshaw, FRSE, FMedSci: Professor of Chromosome Dynamics, School of Biological Sciences. University of Edinburgh.
  3. 8090205. 1994. Lazebnik. Y. A.. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371. 6495. 346–7. Kaufmann. S. H.. Desnoyers. S. Poirier. G. G.. Earnshaw. W. C.. 10.1038/371346a0. 1994Natur.371..346L. 4315478.
  4. 10872455. 1999. Earnshaw. W. C.. Mammalian caspases: Structure, activation, substrates, and functions during apoptosis. Annual Review of Biochemistry. 68. 383–424. Martins. L. M.. Kaufmann. S. H.. 10.1146/annurev.biochem.68.1.383.
  5. 10739650. 2000. Kaufmann. S. H.. Induction of apoptosis by cancer chemotherapy. Experimental Cell Research. 256. 1. 42–9. Earnshaw. W. C.. 10.1006/excr.2000.4838.
  6. Web site: https://web.archive.org/web/20120516041818/http://earnshaw.bio.ed.ac.uk/prof-bill-earnshaw-frse. 2012-05-16. Prof Bill Earnshaw, FRSE, FMedSci. University of Edinburgh.
  7. , University of Edinburgh
  8. PhD . William Charles. Earnshaw . The Structure of Bacteriophage p22 and its Assembly Intermediates . Massachusetts Institute of Technology . 1977 .
  9. 370407. 1978. Earnshaw. W. Structure of phage P22 coat protein aggregates formed in the absence of the scaffolding protein. Journal of Molecular Biology. 126. 4. 721–47. King. J. 10.1016/0022-2836(78)90017-7.
  10. 161330. 1979. Earnshaw. W. C.. Structural studies of bacteriophage lambda heads and proheads by small angle X-ray diffraction. Journal of Molecular Biology. 134. 3. 575–94. Hendrix. R. W.. King. J. 10.1016/0022-2836(79)90368-1.
  11. 688382. 1978. Earnshaw. W. C.. The structural organization of DNA packaged within the heads of T4 wild-type, isometric and giant bacteriophages. Cell. 14. 3. 559–68. King. J. Harrison. S. C.. Eiserling. F. A.. 10.1016/0092-8674(78)90242-8. 9738540.
  12. 682194. 1978. Earnshaw. W. C.. The size of the bacteriophage T4 head in solution with comments about the dimension of virus particles as visualized by electron microscopy. Journal of Molecular Biology. 122. 2. 247–53. King. J. Eiserling. F. A.. 10.1016/0022-2836(78)90040-2.
  13. 7407918. 1980. Earnshaw. W. C.. Assembly of nucleosomes: The reaction involving X. Laevis nucleoplasmin. Cell. 21. 2. 373–83. Honda. B. M.. Laskey. R. A.. Thomas. J. O.. 10.1016/0092-8674(80)90474-2. 25210558.
  14. 6250082. 1980. Laskey. R. A.. Nucleosome assembly. Nature. 286. 5775. 763–7. Earnshaw. W. C.. 10.1038/286763a0. 1980Natur.286..763L. 4373003.
  15. 6201324. 1984. Earnshaw. W. C.. Silver staining the chromosome scaffold. Chromosoma. 89. 3. 186–92. Laemmli. U. K.. 10.1007/bf00294997. 19757611.
  16. 6826654. 2112267. 1983. Earnshaw. W. C.. Architecture of metaphase chromosomes and chromosome scaffolds. The Journal of Cell Biology. 96. 1. 84–93. Laemmli. U. K.. 10.1083/jcb.96.1.84.
  17. 2435739. 2114438. 1987. Earnshaw. W. C.. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. The Journal of Cell Biology. 104. 4. 817–29. Sullivan. K. F.. Machlin. P. S.. Cooke. C. A.. Kaiser. D. A.. Pollard. T. D.. Rothfield. N. F.. Cleveland. D. W.. 10.1083/jcb.104.4.817.
  18. PhD. University of Edinburgh. Hacking the centromere chromatin code : dissecting the epigenetic regulation of centromere identity. Jan H.. Bergmann. 2010. 1842/4670. .
  19. PhD. University of Edinburgh. Genetic and functional analysis of topoisomerase II in vertebrates. Anca. Petruti-Mot. 2000. 1842/8985. .
  20. PhD. University of Edinburgh. Structural and functional mapping of the vertebrate centromere. Susana Abreu. Ribeiro. 2010.
  21. PhD. University of Edinburgh. Understanding kinetochore dependency pathways using vertebrate conditional knockout cell lines and quantitative proteomics. Laura Charlotte. Wood. 2014. ed.ac.uk. . 1842/8964.
  22. PhD. University of Edinburgh. Cellular and molecular analysis of chromosomal passenger complex in vertebrate cells. Zhenjie. Xu. 2009.
  23. PhD. University of Edinburgh. Inner nuclear membrane proteins : targeting and influence on genome organization. Nikolaj. Zuleger. 2012.
  24. Web site: https://web.archive.org/web/20150923075149/https://royalsociety.org/people/william-earnshaw-11373/. Professor William Earnshaw FMedSci FRS. 2015-09-23. Royal Society. London.
  25. Web site: The EMBO Pocket Directory. https://web.archive.org/web/20150316002020/http://www.embo.org/documents/members/The_EMBO_Pocket_Directory.pdf. 2015-03-16. European Molecular Biology Organization.

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