| William B. Woodin | |
| Birth Date: | 25 September 1824 |
| Birth Place: | Genoa, New York |
| Death Place: | Auburn, New York |
| Resting Place: | Fort Hill Cemetery |
| Occupation: | Lawyer, politician |
| Party: | Republican |
| Office: | Member of the New York State Senate |
| Constituency: | 25th District |
| Term Start: | 1870 |
| Term End: | 1877 |
| Predecessor: | Stephen K. Williams |
| Successor: | Theodore M. Pomeroy |
| Term Start1: | 1880 |
| Term End1: | 1881 |
| Constituency1: | 26th District |
| Predecessor1: | Edwin Hicks |
| Successor1: | David H. Evans |
| Office2: | Member of the New York State Assembly |
| Constituency2: | Cayuga County, 3rd District |
| Term Start2: | 1855 |
| Term End2: | 1855 |
| Predecessor2: | Mathias Hutchinson |
| Successor2: | Tolbert Powers |
William B. Woodin (September 25, 1824 – November 1, 1893) was an American lawyer and politician from New York.
William B. Woodin was born in Genoa, New York on September 25, 1824. He attended the district schools, Moravia Academy, and Cortland Academy in Homer. Then he studied law, was admitted to the bar, and commenced practice in Aurora. He was a member of the New York State Assembly (Cayuga Co., 3rd D.) in 1855. After his election as Surrogate, he removed to the county seat Auburn.
He was Surrogate of Cayuga County from 1860 to 1871; and a member of the New York State Senate (25th D.) from 1870 to 1877, sitting in the 93rd, 94th, 95th, 96th, 97th, 98th, 99th and 100th New York State Legislatures. In 1877, he was accused of having taken bribes from William M. Tweed, but a State Senate investigation concluded that he was innocent. Nevertheless, Woodin declined to run for re-election.
He was again a member of the State Senate (26th D.) in 1880 and 1881. He was a delegate to the 1880 Republican National Convention where he opposed Roscoe Conkling's plan to nominate Ulysses S. Grant for a third term. In 1882, Woodin abandoned the Republican candidate for Governor, Charles J. Folger, and supported Democrat Grover Cleveland instead.
He was buried at the Fort Hill Cemetery in Auburn.