| Wharton Creek | |
| Pushpin Map: | New York Adirondack Park#USA |
| Pushpin Map Caption: | Location of the mouth of Wharton Creek |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type3: | Region |
| Subdivision Name3: | Central New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Otsego |
| Subdivision Type5: | Towns |
| Subdivision Name5: | Richfield, Plainfield, Exeter, Burlington, Edmeston, Pittsfield |
| Length: | 36.1miles |
| Mouth: | Unadilla River |
| Mouth Location: | New Berlin |
| Mouth Coordinates: | 42.6182°N -75.3279°W |
| Progression: | Wharton Creek → Unadilla River → Susquehanna River → Chesapeake Bay → Atlantic Ocean |
| Basin Size: | 92.4sqmi[1] |
| Tributaries Left: | Fly Brook, Dundee Brook |
| Tributaries Right: | Mill Creek |
Wharton Creek is a 36.1adj=midNaNadj=mid[2] tributary of the Unadilla River in western Otsego County, in the state of New York. Via the Unadilla River, it is part of the Susquehanna River watershed, flowing to Chesapeake Bay.
Wharton Creek rises in the town of Richfield and flows southwest through the towns of Plainfield, Exeter, Burlington, Edmeston, and Pittsfield, where it empties into the Unadilla River at the village of New Berlin.
Fly Brook converges with Wharton Creek south of Burlington Flats. Dundee Brook converges with Wharton Creek north-northeast of Burlington Flats.[3]