| Seo | |
| Native Name Lang: | ko |
| Settlement Type: | Autonomous District |
| Translit Lang1: | Korean |
| Translit Lang1 Type1: | Hanja |
| Translit Lang1 Info2: | Seo-gu |
| Translit Lang1 Info3: | Sŏ-gu |
| Subdivision Type: | Country |
| Subdivision Name: | South Korea |
| Subdivision Type1: | Region |
| Subdivision Name1: | Hoseo |
| Subdivision Type2: | Provincial level |
| Subdivision Name2: | Daejeon |
| Subdivision Type3: | Administrative divisions |
| Subdivision Name3: | 23 administrative dong |
| Area Total Km2: | 95.25 |
| Population As Of: | 2006[1] |
| Population Total: | 506070 |
| Population Density Km2: | auto |
| Population Blank1 Title: | Dialect |
| Population Blank1: | Chungcheong |
| Leader Party: | People Power |
| Leader Title: | Mayor |
| Leader Name: | Seo Cheol-Mo |
Seo District (Seo-gu) is a gu ("district") of Daejeon, South Korea. Daejeon Metropolitan City Hall is also located there.
Seo-gu is divided into 14 dong (동, "neighborhoods"):
Dunsan-dong is one of the more densely populated areas of Daejeon. As a result, it is the location of several points of interest. These include department stores, government offices, and several international chain restaurants and retailers. There is Pai Chai University in Seo District, Daejeon. There is also Hanbat Arboretum. There is also the "Cafe Wave". There is an Art Center. Jangtae Recreational Forest is located in the district.
Also, Daejeon Arts Center, a representative general concert hall in Daejeon, is also located in Seo-gu.