| Weeds Brook | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Weeds Brook |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Delaware |
| Source1 Coordinates: | 42.1411°N -75.0536°W |
| Mouth: | West Branch Delaware River |
| Mouth Coordinates: | 42.1604°N -75.0724°W[1] |
| Mouth Elevation: | 1217feet |
Weeds Brook is a river in Delaware County, New York. It flows into the West Branch Delaware River east of Walton.