Webe Kadima Explained

Webe Celine Kadima (born 1958) is an associate professor of chemistry at the State University of New York at Oswego.^{[1] [2]}

Early life

Kadima was born in Burundi and moved to the Democratic Republic of Congo when she was 4 years old.^[3] She had to get the support of a government official to be included in the chemistry program at the University of Kinshasa, and after a year there she transferred to the University of Montreal, from which she graduated with a degree in chemistry.^[4] Her father was a diabetic and died from complications from diabetes while she was at the University of Montreal.^[5] She eventually obtained a in bioanalytical chemistry from the University of Alberta.^[4] In her research for it she discovered that cadmium binds within the red blood cell mostly to glutathione and to a lesser degree to hemoglobin.^[4]

Career

After graduating from the University of Alberta, Kadima held several different teaching positions and eventually became a professor at the State University of New York at Oswego.^{[3] [4]} In 2004 she went back to the Congo for a sabbatical to collaborate on research projects, concentrating her research on plants used in the Congo to treat diabetes.^[4] She created a nonprofit called the Bioactive Botanical Research Institute, whose mission was to investigate medicinal plants used in the Congo and to develop pharmaceutical preparations that would be affordable, useful, and safe.^[4] She has also worked to create an ongoing exchange of African students with the State University of New York at Oswego.^[6] In 2010 it was announced that she had received a $200,000 National Science Foundation grant for the study of how to expand the number of women in science.^{[7] [8]}

In July 1983, she published the results of her research on a proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes together with Rabenstein, Isab and Mohanakrishnan.^[9] She was later first author on a paper looking at the stability of the cadmium-glutathione complex in hemolysed red blood cells.^[10] In the Inorganica Chimica Acta she published an article about the kinetics of palladium ethylenediamine chloride in solution.^[11]

Scientific publications

• Webe Kadima and Michael Hanson: A NMR Study of the T3R3 to R6 Allosteric Transition in the Iron-substituted Insulin Hexamer. Working Paper, Jan 2017.^[12]
• Webe Kadima, Angela Nugroho, Deborah Kerwood and Phil Borer: The T- to R-Allosteric Transition in the Cadmium-substituted Insulin Hexamer. Research, Jan 2016.^[12]
• Webe Kadima: Diabetes Screening in Kinshasa, Democratic Republic of Congo. Research, Jan 2016.^[12]
• Helle Birk Olsen, Melissa R Leuenberger-Fisher, Webe Kadima, [...], Michael F Dunn: Structural signatures of the complex formed between 3-nitro-4-hydroxybenzoate and the Zn(II)-substituted R 6 insulin hexamer. Oct 2003, Protein Science.^[12]
• Webe Kadima: Role of Metal Ions in the T- To R-Allosteric Transition in the Insulin Hexamer. Nov 1999, Biochemistry.^[12]
• W. Kadima, P. Raharivelomanana and B. Bechtel: The binding of cyclic adenosine 3′, 5′ monophosphate to the insulin hexamer. Jan 1997, Protein and Peptide Letters.^[12]
• W Kadima, L Ogendal, R Bauer, [...] and P Porting: The influence of ionic strength and pH on the aggregation properties of zinc-free insulin studied by static and dynamic laser light scattering. Biopolymers. Dec 1993, Biopolymers.^[12]
• W Kadima, M Roy, R. W. K. Lee, [...], M F Dunn: Studies of the association and conformational properties of metal-free insulin in alkaline sodium chloride solutions by one- and two-dimensional 1H NMR. Jun 1992, Journal of Biological Chemistry.^[12]
• Webe Kadima, Alexander McPherson, Michael F. Dunn and Frances Jurnak: Precrystallization aggregation of insulin by dynamic light scattering and comparison with canavalin. Mar 1991, Journal of Crystal Growth.^[12]
• Webe Kadima and Dallas L. Rabenstein: A quantitative study of the complexation of cadmium in hemolyzed human erythrocytes by 1H NMR spectroscopy. Nov 1990, Journal of Inorganic Biochemistry.^[12]
• Webe Kadima and Dallas L. Rabenstein: Nuclear magnetic resonance studies of the solution chemistry of metal complexes. 26. Mixed ligand complexes of cadmium, nitrilotriacetic acid, glutathione, and related ligands. J Inorg Biochem. May 1990, Journal of Inorganic Biochemistry.^[12]
• W Kadima, A McPherson, M F Dunn and F.A. Jurnak: Characterization of precrystallization aggregation of canavalin by dynamic light scattering. Feb 1990, Biophysical Journal.^[12]
• Karl F. Houben, Webe Kadima, Melinda Roy and Michael F. Dunn: L-Serine analogs form Schiff base and quinonoidal intermediates with Escherichia coli tryptophan synthase. May 1989, Biochemistry.^[12]
• Dallas L. Rabenstein, Anvarhusein A. Isab, Webe Kadima and P Mohanakrishnan: A proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes. Aug 1983, Biochimica et Biophysica Acta.^[12]
• W. Kadima and M. Zador: Kinetics on interaction of Pd(en)Cl2 with inosine in chloride containing aqueous solutions. Jan 1983, Inorganica Chimica Acta.^[12]
• Webe Celine Kadima: NMR studies of the interaction of Cd(II) with ligands of biological interest and with red blood cells.^[12]

Notes and References

1. https://www.oswego.edu/chemistry/faculty-and-staff Faculty and staff
2. Web site: Webe Celine Kadima . Oswego.edu . 2016-07-21 . https://web.archive.org/web/20160726175228/https://www.oswego.edu/experts-guide/content/webe-celine-kadima . 2016-07-26 . dead .
3. Web site: Nicholas Lisi / The Post-Standard . Oswego State professor delves into plant use to treat diabetes . syracuse.com . 2011-06-05 . 2016-05-25.
4. Book: Henry Louis Jr.. Gates. Henry Louis Gates Jr.. Emmanuel . Akyeampong. Emmanuel K. Akyeampong. Steven J.. Niven. Dictionary of African Biography. Kadima, Webe (1958–). https://books.google.com/books?id=39JMAgAAQBAJ&pg=RA2-PA257. 2 February 2012. Oxford University Press. 978-0-19-538207-5. 257–258.
5. Web site: Student researcher helps study plants that could aid diabetics . Oswego.edu . 2011-04-06 . 2016-07-21 . https://web.archive.org/web/20160726175231/http://www.oswego.edu/news/index.php/site/news_story/kadima_study . 2016-07-26 . dead .
6. Web site: Fulbright Scholar Faith Maina to Educate Researchers in Kenya . Mwakilishi.com . 2016-03-15 . 2016-05-25 . https://web.archive.org/web/20160726175234/http://www.mwakilishi.com/content/articles/2013/07/09/fulbright-scholar-faith-maina-to-educate-researchers-in-kenya.html . 2016-07-26 . dead .
7. National Science Foundation: Award Abstract #1008535: Recruiting, Retaining, and Promoting Women in STEM Fields: Preparing for an Institutional Transformation Grant.
8. Web site: Diversity Increases Among New Faculty, Staff, Students . The Oswegonian . 2010-10-14 . 2016-07-21.
9. Rabenstein. Dallas L.. Isab. Anvarhusein A.. Kadima. Webe. Mohanakrishnan. P.. A proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. July 1983. 762. 4. 531–541. 10.1016/0167-4889(83)90057-5. 6409155.
10. Kadima. Webe. Rabenstein. Dallas L.. A quantitative study of the complexation of cadmium in hemolyzed human erythrocytes by1H NMR spectroscopy. Journal of Inorganic Biochemistry. October 1990. 40. 2. 141–149. 10.1016/0162-0134(90)80047-2. 2128706.
11. Kadima. W.. Zador. M.. Kinetics on interaction of Pd(en)Cl2 with inosine in chloride containing aqueous solutions. Inorganica Chimica Acta. January 1983. 78. 97–101. 10.1016/S0020-1693(00)86496-8.
12. Web site: Publications by Webe Kadima listed at ResearchGate..