| Position: | Running back |
| Number: | 30 |
| Birth Date: | 1 September 1946 |
| Birth Place: | Gainesville, Florida, U.S. |
| Death Place: | Buffalo, New York, U.S. |
| Height Ft: | 6 |
| Height In: | 2 |
| Weight Lbs: | 254 |
| Draftyear: | 1968 |
| Draftround: | 10 |
| Draftpick: | 247 |
| High School: | Lincoln (Gainesville, FL) |
| College: | Louisville |
| Pastteams: |
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| Statlabel1: | Rushing attempts-yards |
| Statvalue1: | 264–1084 |
| Statlabel2: | Receptions-yards |
| Statvalue2: | 96–745 |
| Statlabel3: | Touchdowns |
| Statvalue3: | 6 |
| Pfr: | PatrWa00 |
Wayne Allen Patrick (September 1, 1946 – March 23, 2010) was a professional American football running back for five seasons for the Buffalo Bills in both the American Football League (AFL) and the National Football League (NFL). He was born in Gainesville, Florida. He settled in Amherst, a suburb of Buffalo after retiring from football and raised his family. He married Mary Richard and had four children Wayne JR, Melissa, Jadah, and Joel. He died on March 23, 2010, after a lengthy battle with heart and kidney disease.