| Wayne Matherne | |
| Birth Date: | 6 May 1949 |
| Birth Place: | Louisiana, U.S. |
| Import: | yes |
| Height Ft: | 6 |
| Height In: | 1 |
| Weight Lbs: | 195 |
| Position1: | Defensive back |
| Career Highlights: |
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| Playing Years1: | - |
| Playing Team1: | BC Lions |
| Playing Years2: | - |
| Playing Team2: | Edmonton Eskimos |
Wayne Jude Matherne (born May 6, 1949) is a former Canadian football player who played for the BC Lions and Edmonton Eskimos. He won the Grey Cup with Edmonton in 1975. His nickname was "the Ragin' Cajun".[1] He played college football at Northeastern Louisiana University.