| Wayne Brenkert | |
| Image Upright: | 122 |
| Birth Date: | 5 March 1898 |
| Birth Place: | Highland Park, Michigan, U.S. |
| Death Date: | [1] |
| Death Place: | Eustis, Florida, U.S. |
| Height Ft: | 5 |
| Height In: | 10 |
| Weight Lbs: | 170 |
| Position1: | Halfback, quarterback |
| College: | Washington & Jefferson |
| Coachpfr: | BrenWa0 |
| Nfl: | 2510138 |
| Playing Years1: | 1923–1924 |
| Playing Team1: | Akron Pros |
| Coaching Years1: | 1923–1924 |
| Coaching Team1: | Akron Pros |
Wayne Dewey Brenkert (March 5, 1898 – August 1, 1979) was a professional American football player-coach for the Akron Pros. Prior to his professional career, he attended Washington & Jefferson College.