| Wassa Amenfi East Municipal District | |
| Settlement Type: | Municipal District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Wassa Amenfi East Municipal District within Western |
| Subdivision Type: | Country |
| Subdivision Name: |  Ghana |
| Subdivision Type1: | Region |
| Subdivision Name1: | Western |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Wassa-Akropong |
| Leader Title: | Municipal Chief Executive |
| Leader Name: | Hon. Helena Appiah |
| Area Total Km2: | 1729 |
| Population As Of: | 2021 census[1] |
| Population Total: | 179,696 |
| Population Density Km2: | auto |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 5.773°N -2.092°W |
| Iso Code: | GH-WP-WE |
Wassa Amenfi East Municipal District is one of the fourteen districts in Western Region, Ghana. Originally it was formerly part of the then-larger Wassa Amenfi District in 1988, which was created from the former Aowin-Amenfi District Council, until the eastern part of the district was split off to create Wassa Amenfi East District in August 2004; thus the remaining part has been renamed as Wassa Amenfi West District. However, on 15 March 2018, it was later elevated to municipal district assembly status to become Wassa Amenfi East Municipal District. The municipality is located in the northern part of Western Region and has Wassa-Akropong as its capital town.