| Wampum Run | |
| Name Other: | Tributary to Beaver River |
| Map Size: | 300 |
| Pushpin Map: | USA Pennsylvania#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Wampum Run mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States of America |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania |
| Subdivision Type3: | County |
| Subdivision Name3: | Lawrence |
| Length: | 2.49miles[1] |
| Discharge1 Avg: | 3.06cuft/s at mouth with Beaver River[2] |
| Source1: | divide between Wampum Run and North Fork Little Beaver Creek |
| Source1 Location: | about 2 miles south of Coverdale, Pennsylvania |
| Source1 Coordinates: | 40.8614°N -80.3628°W[3] |
| Source1 Elevation: | 1120feet[4] |
| Mouth: | Beaver River |
| Mouth Location: | Wampum, Pennsylvania |
| Mouth Coordinates: | 40.8881°N -80.3358°W |
| Mouth Elevation: | 740feet |
| Progression: | Beaver River → Ohio River → Mississippi River → Gulf of Mexico |
| River System: | Beaver River |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | unnamed tributaries |
Wampum Run is a tributary of the Beaver River in western Pennsylvania. The stream rises in south-central Lawrence County and flows northeast entering the Beaver River at Wampum, Pennsylvania. The watershed is roughly 11% agricultural, 83% forested and the rest is other uses.[2]