Walter Bodmer Explained

Honorific Prefix:Sir
Walter Bodmer
Birth Name:Walter Fred Bodmer
Birth Date:1936 1, df=yes
Birth Place:Frankfurt, Nazi Germany
Education:Manchester Grammar School
Alma Mater:University of Cambridge (BA, PhD)
Thesis Title:The study of population genetics and gene effects, with special reference to Primula vulgaris and the house mouse
Thesis Url:http://search.proquest.com/docview/301236655/
Thesis Year:1959
Doctoral Advisors:)-->
Academic Advisors:Ronald Fisher
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Sir Walter Fred Bodmer (born 10 January 1936[1]) is a German-born British human geneticist.[2] [3] [4] [5] [6] [7]

Early life

Bodmer was born in Frankfurt, Germany.[8] He was educated at Manchester Grammar School and went on to study the Mathematical Tripos at the University of Cambridge as a student of Clare College, Cambridge. He was awarded his PhD in 1959 from Cambridge for research on population genetics in the house mouse and Primula vulgaris (primrose) supervised by Ronald Fisher.

Career and research

In 1961 Bodmer joined Joshua Lederberg's laboratory in the genetics department of Stanford University as a postdoctoral researcher, continuing his work on population genetics.[9] In 1962 Walter Bodmer was appointed to the faculty at Stanford. He left Stanford University in 1970 to become the first professor of genetics at the University of Oxford http://www.hertford.ox.ac.uk/index.php?option=com_content&task=view&id=490&Itemid=581.[10]

Bodmer developed models for population genetics and worked on the human leukocyte antigen system and the use of somatic cell hybrids for human linkage studies. In 1985 he chaired a Royal Society committee which wrote The Bodmer Report; this has been credited[11] with starting the movement for the public understanding of science.[12]

Bodmer was one of the first to suggest the idea of the Human Genome Project.[13] In 1987 he received the Ellison-Cliffe Medal from the Royal Society of Medicine. He was the director of research (1979–1991) and then director general (1991–1996) of the Imperial Cancer Research Fund. He was also chancellor of the University of Salford, England (1995–2005; succeeded by Sir Martin Harris) and principal of Hertford College, Oxford (1996–2005; succeeded by Dr. John Landers).

In 2005, Bodmer was appointed to lead a £2.3 million project (roughly US$4.5 million) by the Wellcome Trust at the University of Oxford to examine the genetic makeup of the United Kingdom – the People of the British Isles project. He was joined by Oxford Professor Peter Donnelly (a population genetics and statistics expert) and the Wellcome Trust Principal Research Fellow Lon Cardon. Bodmer said, "Our aim is to characterise the genetic make-up of the British population and relate this to the historical and archaeological evidence." The researchers presented some of their findings to the public via the Channel 4 television series "Faces of Britain". On 14 April 2007, Channel 4 in Britain aired a program that highlighted the study's then-current findings. The project took DNA samples from hundreds of volunteers throughout Britain, seeking tell-tale fragments of DNA that would reveal the biological traces of successive waves of colonisers – Celts, Saxons, Vikings, etc. – in various parts of Britain. The findings showed that the Viking invasion of Britain was predominantly from Danish Vikings while the Orkney Islands were settled by Norwegian Vikings. This research was most recently presented at the Galton Institute's conference on 'New Light on Old Britons' in 2019.[14] Bodmer had previously worked with the Galton Institute as its president from 2008 to 2014.[15]

He has been head of the cancer and immunogenetics laboratory in the Weatherall Institute of Molecular Medicine at the University of Oxford since 1996.[16] Research interests of the laboratory include the fundamental genetics and biology of colorectal cancer.

Honours and awards

Bodmer has won numerous awards including:

His certificate of election to the Royal Society reads:[18]

Personal life

Bodmer's father was Jewish so the family were obliged to leave Nazi Germany; in 1938, they settled in Manchester, England. In 1956, Walter Bodmer married Julia Bodmer (née Pilkington) 1934–2001; she also became a well-known geneticist. They had two sons and a daughter. Lady Bodmer died in 2001.

Interviews

External links

Notes and References

  1. http://www.timesonline.co.uk/tol/life_and_style/court_and_social/article5484753.ece The Times
  2. 25788095. 2015. Leslie. S. The fine-scale genetic structure of the British population. Nature. 519. 7543. 309–14. Winney. B. Hellenthal. G. Davison. D. Boumertit. A. Day. T. Hutnik. K. Royrvik. E. C.. Cunliffe. B. Wellcome Trust Case Control Consortium 2. International Multiple Sclerosis Genetics Consortium. Lawson. D. J.. Falush. D. Freeman. C. Pirinen. M. Myers. S. Robinson. M. Donnelly. P. Bodmer. W. 10.1038/nature14230. 4632200. 2015Natur.519..309..
  3. 1699228. 54786. 1990. Rodrigues. N. R.. P53 mutations in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 87. 19. 7555–9. Rowan. A. Smith. M. E.. Kerr. I. B.. Bodmer. W. F.. Gannon. J. V.. Lane. D. P. . 10.1073/pnas.87.19.7555. 1990PNAS...87.7555R. free.
  4. Web site: https://web.archive.org/web/20150417112902/http://www.imm.ox.ac.uk/walter-bodmer-2 . Prof Sir Walter Bodmer FRS, Weatherhall Institute for Molecular Medicine. 17 April 2015 . University of Oxford.
  5. Web site: https://web.archive.org/web/20150304080758/http://www.oncology.ox.ac.uk/research/sir-walter-bodmer. 4 March 2015. Walter Bodmer: Cancer and Immunogenetics Laboratory. University of Oxford.
  6. 10.1038/34432. 1998. Nature. 391. 6663. 184–7. Hemminki . A. . Markie . D. . Tomlinson . I. . Avizienyte . E. . Roth . S. . Loukola . A. . Bignell . G. . Warren . W. . Aminoff . M. . Höglund . P. . Järvinen . H. . Kristo . P. . Pelin . K. . Ridanpää . M. . Salovaara . R. . Toro . T. . Bodmer . W.. Walter Bodmer . Olschwang . S. . Olsen . A. S. . Stratton . M. R. . Michael Stratton. de la Chapelle . A. . Aaltonen . L. A. . A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.. 9428765. 1998Natur.391..184H. 4400728.
  7. 18509313. 2527050. 2008. Bodmer. W. Common and rare variants in multifactorial susceptibility to common diseases. Nature Genetics. 40. 6. 695–701. Bonilla. C. 10.1038/ng.f.136.
  8. Web site: BSI HONORARY MEMBER: Sir Walter Bodmer. https://web.archive.org/web/20150402172312/https://www.immunology.org/sslpage.aspx?pid=1194. 2 April 2015. British Society of Immunology.
  9. Web site: Early Computers at Stanford. https://web.archive.org/web/20140813185609/http://forum.stanford.edu/wiki/index.php/Early_Computers_at_Stanford. 13 August 2014. Stanford University.
  10. Conversation with Walter Bodmer, San Francisco, 4 Dec.2010
  11. Book: Sloman . Steven . Fernbach . Philip . The Knowledge Illusion . 2017 . Macmillan . London . 978-1-5098-1106-9 . 157.
  12. Web site: https://web.archive.org/web/20131019050128/http://royalsociety.org/WorkArea/DownloadAsset.aspx?id=5971. Public Understanding of Science, 1985. Royal Society. 19 October 2013.
  13. Web site: https://web.archive.org/web/20150408001521/http://www.hugo-international.org/abt_hugopresidents.php. 8 April 2015. HUGO presidents.
  14. Web site: Past Events – The Galton Institute. 2020-11-18. en-US.
  15. Web site: Past Presidents – The Galton Institute. 2020-11-18. en-US.
  16. Web site: Walter Bodmer. 2020-12-02. en-US.
  17. Web site: Walter Fred Bodmer . 13 October 2023 .
  18. Web site: EC/1974/01: Bodmer, Walter Fred . The Royal Society . 15 October 2015 . https://web.archive.org/web/20151015190008/https://collections.royalsociety.org/DServe.exe?dsqIni=Dserve.ini&dsqApp=Archive&dsqDb=Catalog&dsqCmd=show.tcl&dsqSearch=(RefNo

    %27EC%2F1974%2F01%27)

    . London . dead . dmy-all .
  19. Web site: https://web.archive.org/web/20151009144644/https://royalsociety.org/people/walter-bodmer-11105/. 9 October 2015. Sir Walter Bodmer FMedSci FRS. Royal Society. London.
  20. Web site: Walter Bodmer .
  21. Web site: Honorary Graduates 1989 to present . bath.ac.uk . . 18 February 2012.
  22. Web site: | British Society for Immunology.