| Walker Brooke | |
| Term Start: | February 4, 1861 |
| Term End: | February 17, 1862 |
| Predecessor: | New constituency |
| Successor: | Constituency abolished |
| Jr/Sr2: | United States Senator |
| Term Start2: | February 18, 1852 |
| Term End2: | March 3, 1853 |
| Term Start4: | 1850 |
| Term End4: | 1852 |
| Term5: | 1848 |
| Birth Date: | 25 December 1813 |
| Birth Place: | Clarke County, Virginia, U.S. |
| Death Place: | Vicksburg, Fourth Military District, U.S. |
| Resting Place: | Cedar Hill Cemetery, Vicksburg, Mississippi |
| Alma Mater: | University of Virginia |
Walker Brooke (December 25, 1813 – February 18, 1869) was an American politician who served as a Deputy from Mississippi to the Provisional Congress of the Confederate States from 1861 to 1862. He was also a U.S. Senator from 1852 to 1853, representing the state of Mississippi.
Born on December 25, 1813, in Clarke County, Virginia, Walker Brooke was the son of Humphrey Brooke and Sarah Walker Page. He attended the public schools in Richmond, Virginia and Georgetown, D.C. He graduated from the University of Virginia at Charlottesville in 1835, studied law, was admitted to the bar in 1838 and commenced practice in Lexington, Mississippi. He was a member of the Mississippi House of Representatives in 1848 and was a member of the Mississippi Senate in 1850 and 1852.
Brooke was elected as a Whig to the U.S. Senate to fill the vacancy caused by the resignation of Henry S. Foote and served from February 18, 1852, to March 3, 1853; he was not a candidate for reelection and resumed the practice of law. In 1857 he moved to Vicksburg and continued the practice of law; he was a delegate to the constitutional convention in 1861 and became affiliated with the Democratic Party that year. He was elected a member of the Provisional Congress of the Confederate States from Mississippi in 1861 and served one year; he was then appointed a member of the permanent military court of the Confederate States.