| W. B. Hopkins | |
| Birth Date: | 1 January 1869 |
| Birth Place: | Ontario, New York, U.S. |
| Death Place: | Marion, New York, U.S. |
| Player Years1: | 1893–1894 |
| Player Team1: | Brown |
| Coach Years1: | 1899 |
| Coach Team1: | Maine |
| Overall Record: | 2–3 |
William Burr Hopkins (January 1, 1869 – December 6, 1935) was the head coach of the University of Maine's football team in 1899 and compiled a 2–3 record.
Hopkins was born in 1869 to Burton and Anna (née Sprague) Hopkins. He was captain of the Brown University football teams of 1893 and 1894. After Brown, he worked as an engineer in Pennsylvania before serving overseas in France for World War I. After his return, he married Fanny Schinsing in 1921 and worked as a farmer until his death in 1935 after a horse accident.[1]