The W.O. Mitchell Literary Prize was a Canadian literary award, presented by the Writers' Trust of Canada to a writer who produced an outstanding body of work, acted during his/her career as a "caring mentor" for writers, and published a work of fiction or had a new stage play produced during the three-year period specified for each competition. The rules of the prize stipulated that every third year the winner be francophone. The prize is no longer awarded.
The prize was named in memory of Canadian writer W.O. Mitchell, who died in 1998.