| Vitry-le-François | |
| Commune Status: | Subprefecture and commune |
| Image Coat Of Arms: | Blason ville fr Vitry-le-François 51.svg |
| Arrondissement: | Vitry-le-François |
| Canton: | Vitry-le-François-Champagne et Der |
| Insee: | 51649 |
| Postal Code: | 51300 |
| Mayor: | Jean-Pierre Bouquet[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Vitry, Champagne et Der |
| Coordinates: | 48.7256°N 4.5853°W |
| Elevation M: | 105 |
| Area Km2: | 6.45 |
Vitry-le-François (in French pronounced as /vitʁi lə fʁɑ̃swa/) is a commune in the Marne department in northeastern France. It is located on the river Marne and is the western terminus of the Marne–Rhine Canal. Vitry-le-François station has rail connections to Paris, Reims, Strasbourg, Metz, Dijon and several regional destinations.
The present town is a relatively recent construction, having been built in 1545 at the behest of King Francis who wished to replace, on a new site, Vitry-en-Perthois, which in 1544 had been entirely destroyed as part of the backwash from the king's Italian War of 1542–46. The new Vitry was to be a modern city, constructed according to a plan produced by Girolamo Marini. The king's role in its creation resulted in Vitry-le-François receiving the king's name as part of its own name.
At the beginning of World War I in August 1914, Joseph Joffre established the Grand Quartier Général at the Place Royer-Collard.
In 1961, a terrorist attack took place on a train going between Strasbourg and Paris.
Vitry-le-François is twinned with: