| Vitale De Stefano | |
| Birth Date: | 4 May 1889 |
| Birth Place: | Acireale, Sicily, Kingdom of Italy |
| Death Date: | 9 February 1959 |
| Death Place: | Milan, Lombardia, Italy |
| Othername: | Vitale Di Stefano |
| Birth Name: | Vitale Gioacchino De Stefano |
| Occupation: | Actor, Director |
| Yearsactive: | 1909–1942 |
Vitale De Stefano (1889–1959) was an Italian actor and film director of the silent era. He played the role of Masinissa in Giovanni Pastrone's epic Cabiria in 1914.[1]