| Genre: | Supernatural |
| Language: | Hindi |
| Country: | India |
| Director: | Alind Srivastava Nissar Parvej |
| Starring: | Aishwarya Khare Vin Rana |
| Camera: | Multi-camera |
| Channel: | Zee TV, &TV |
| Company: | Peninsula Pictures |
| Num Seasons: | 1 |
| Num Episodes: | 143 |
Vishkanya Ek Anokhi Prem Kahani or simply Vishkanya (lit. venomous girl) is a soap set in the old neighbourhood of the city of Kolkata.[1] The show is about supernatural love story of fictional characters Aparajita Ghosh and Malay Mittal.
Aparajita aka Appu is born as a Vishkanya, a venomous girl, whose body and bodily fluids are poisonous and could prove fatal for anyone on contact. Initially she was not aware of the fact that she was a poisonous girl or that she was used as a pawn to destroy the Mittal family by her maternal aunt, Kalpana Ghosh, who she believes to be her mother. Kalpana kept her locked in her room since she was a little girl, avoiding any contact with outsiders. This ignited curiosity from her neighbors, especially Malay.
The first time she was allowed out was for a party in Mittal's mansion, where she met Malay for the first time. Malay was instantly smitten by her beauty and delicate grace despite her mysterious aura. A series of events led Appu to begin questioning her true identity. She demanded answers from Kalpana about the unexplained facts such as her skin turning blue whenever she was distressed. Kalpana revealed that she was a descendant of Vishkanya. For generations, daughters in her family were used as a weapon to destroy kingdoms and cities. Kalpana urges her to kill each and every member of Mittal family, especially Malay to hurt his mother. Years ago, Malay's father married Kalpana despite already being married to Malay's mother, Nandita. Enraged, Nandita hired a man to kill Kalpana but he mistakenly harms Kalpana's sister and Appu’s mother, Niranjana, causing Malay's father and Niranjana to be paralyzed.
Kalpana swore revenge Nandita Mittal by planning to make Malay fall in love with Appu and then dispose of him later. Appu was disturbed by the fact but she could not find it in her heart to do as Kalpana asked and distanced herself from him. Malay, however, kept relentlessly pursuing her without knowing the reason. Against all odds, they both fell for each other, but Nandita plotted many evil schemes to separate them. Nandita hires her brothers to kill Appu and bury her to stop her from marrying Malay. They brutally torture her and leave her to die in acid underground.
In the end, Malay reluctantly marries Vardaan due to some misunderstanding caused by his mother and under the influence of the rest of his family. In the sequence of events, Malay has a change of heart and begins to love Vardaan, much to Appu's dismay as he instantly breaks up with her after that. Finally, Appu decides to seek revenge against the Mittal family for everything she has suffered. By some tricks she had up her sleeves and with Kalpana's aid, Appu manages to marry Malay but at this point he does not love her anymore and still remains unaware of her supernatural identity. Vardaan divorces Malay under the influence of Appu, and Malay is then forced to marry Appu. Vardaan saves Appu's life and Appu decides to let Vardaan and Malay be together.
Appu tells Vardaan about her supernatural identity. Just before Malay and Vardaan's wedding, Kasturi (Assistant of Kala Saaya, the head of all evil) comes to kill Appu but Vardaan comes in the way and saves Appu. Appu manages to kill Kasturi. Before dying, Vardaan makes Appu promise to take care of Malay.
The show takes a 3-month leap and introduces Mandira, Nandita's sister who is killed by Kala Saaya.
Kala Saaya takes Mandira's form and comes to the Mittal Mansion where she kills Chiki, Avi's fiancée. Kala Saaya (who is made up of smoke) calls her another assistant, Yakshini, who is the embodiment of lust. Yakshini comes to Mittal Mansion as Laila, who is to marry Avi. Appu finds them suspicious and she manages to burn Yakshini's house, a tree. (It is believed that a Yakshini's powers are in its house) Kala Saaya kidnaps Kalpana and orders Appu to get intimate with Malay as Appu's offspring will free her from old-age curse and will give her powers. Malay heard them talking and Malay and Appu pretend that they got intimate and fake Malay's death (as getting intimate with a Vishkanya results in death). Appu tells Kala Saaya to let her meet her aunt and she agrees.
There, Appu kills Kala Saaya and she decides to go to Himalayas and spend her life there. Malay realises his love for Appu and stops her. Then Baba (Priest) comes with a rabbit and orders Appu to kill it. Appu scratches it but nothing happens, then Baba tells her that Goddess has taken her venom out of her body in return of Kala Saaya’s death and now she can live in peace. Appu and Malay get married and they live together, happily.