Viridiflorol Explained

Viridiflorol is a chemical compound, classified as a sesquiterpenoid, that has been isolated from the essential oils of a variety of plants including Melaleuca quinquenervia^[1] (broad-leaved paperbark), Melaleuca alternifolia^[2] (tea tree), and Allophylus edulis.^[3]

Viridiflorol has shown moderate antibacterial activity against Mycobacterium tuberculosis, the causative agent of tuberculosis, in an in vitro assay. ^[1] It is also produced by the endophytic root fungus Serendipita indica and exhibits antifungal activity against Colletotrichum truncatum ^[4]

Notes and References

1. 10.1016/s0305-1978(01)00112-0 . Chemical variation in the leaf essential oil of Melaleuca quinquenervia (Cav.). It is also produced by the endopytic fungus Serendipita indica S.T. Blake . Biochemical Systematics and Ecology . 30 . 5 . 457–470 . 2002 . Ireland . B.F. . Hibbert . D.B. . Goldsack . R.J. . Doran . J.C. . Brophy . J.J. .
2. Web site: Essential oil of Melaleuca, terpene-4-ol (tea tree oil): ISO 4730: 2017 (E) . International Organization for Standardization (ISO), Geneva, Switzerland . 6 March 2019 . 2017.
3. 10.1016/j.jep.2016.08.053 . 27612433 . Anti-inflammatory, antioxidant and anti- Mycobacterium tuberculosis activity of viridiflorol: The major constituent of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk . Journal of Ethnopharmacology . 192 . 510–515 . 2016 . Trevizan . Lucas Noboru Fatori . Nascimento . Kamilla Felipe do . Santos . Joyce Alencar . Kassuya . Candida Aparecida Leite . Cardoso . Claudia Andrea Lima . Vieira . Maria do Carmo . Moreira . Flora Martinez Figueira . Croda . Julio . Formagio . Anelise Samara Nazari .
4. 10.3390/biom11060898 . A Sesquiterpene Synthase from the Endophytic Fungus Serendipita indica Catalyzes Formation of Viridiflorol. . Biomolecules . 11 . 898 . 2021 . Ntana . F. . Bhat . W.W. . Johnson . S.R. . Jørgensen . H.J.L. . Collinge . D.B. . Jensen . B. . Hamberger . B.. 6 . free . 34208762 . 8234273 .