1,1,2-Trichloroethane Explained

1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula and the structural formula . It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.[1]

Toxicity

1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.[2]

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-Trichloroethane at 10 ppm over an eight-hour time-weighted average.[3]

Notes and References

  1. Toxicological profile for 1,1,2-trichloroethane . Agency for Toxic Substances and Disease Registry (ATSDR) . March 2021 . 2023-08-23 . 2022-03-05 . https://web.archive.org/web/20220305233413/https://www.atsdr.cdc.gov/toxprofiles/tp148.pdf . live.
  2. Web site: Safety (MSDS) data for 1,1,2-trichloroethane .
  3. https://www.cdc.gov/niosh/npg/npgd0628.html CDC - NIOSH Pocket Guide to Chemical Hazards