| Villotte-Saint-Seine | |
| Commune Status: | Commune |
| Arrondissement: | Dijon |
| Canton: | Fontaine-lès-Dijon |
| Insee: | 21705 |
| Postal Code: | 21690 |
| Mayor: | Sandra Graillot[1] |
| Term: | 2023 - 2026 |
| Coordinates: | 47.4297°N 4.7067°W |
| Elevation M: | 350 |
| Elevation Min M: | 338 |
| Elevation Max M: | 551 |
| Area Km2: | 7.59 |
Villotte-Saint-Seine (in French pronounced as /vilɔt sɛ̃ sɛn/) is a commune in the Côte-d'Or department in eastern France.