| Official Name: | Villadepera |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Villadepera |
| Area Total Km2: | 30.11 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
Villadepera de Sayago is a rural municipality of the Spanish Zamora Province. On January 1, 2001 Villadepera had a total population of 282.
Villadepera is situated in a region where the Douro forms narrow canyons for 112 km, and that has now a protected status as the International Douro Natural Park.