Vijayalakshmi Ravindranath Explained

Vijayalakshmi Ravindranath
Birth Date:18 October 1953
Birth Place:Chennai, India
Nationality:Indian
Fields:Neuroscience
Workplaces:Indian Institute of Science, National Brain Research Centre, National Institute of Mental Health and Neurosciences, Centre for Brain Research
Alma Mater:Andhra University, Mysore University
Doctoral Advisor:Chandrasekhara N
Known For:Promoting neuroscience research and establishing major neuroscience research centres in India

Vijayalakshmi Ravindranath (born 18 October 1953) is an Indian neuroscientist. She is currently a professor at the Centre for Neuroscience, Indian Institute of Science in Bangalore. She was the founder director of the National Brain Research Centre, Gurgaon (2000-9) and founder chair of the Centre for Neuroscience at Indian Institute of Science. Her main area of interest is the study of brain related disorders including neurodegenerative diseases such as Alzheimer's and Parkinson's.[1] [2] She serves as the founding director of the Centre for Brain Research in Bangalore.[3]

Education and career

Ravindranath earned her B.Sc. and M.Sc. degrees from Andhra University, received her Ph.D. in biochemistry in 1981 from Mysore University, and worked at the National Cancer Institute in the US as a postdoctoral fellow. She joined the National Institute of Mental Health and Neurosciences in Bangalore, where she studied the metabolizing capacity of the human brain, focusing especially on psychoactive drugs and environmental toxins.[4] In 1999, she helped Department of Biotechnology of the Government of India to establish National Brain Research Centre to co-ordinate and network neuroscience research groups in India.[5]

Awards and recognitions

Ravindranath is an elected fellow of several Indian academies: Indian Academy of Sciences, National Academy of Sciences, Indian National Science Academy and National Academy of Medical Sciences,[6] Indian Academy of Neurosciences and Third World Academy ofSciences.[7]

Publications

Ravindranath, V., & Sundarakumar, J. S. (2021). Changing demography and the challenge of dementia in India. In Nature Reviews Neurology (Vol. 17, Issue 12, pp. 747–758). Nature Research. https://doi.org/10.1038/s41582-021-00565-x

  1. 10.1089/ars.2015.6602. 27121974. Thiol Oxidation by Diamide Leads to Dopaminergic Degeneration and Parkinsonism Phenotype in Mice: A Model for Parkinson's Disease. Antioxidants & Redox Signaling. 25. 5. 252–267. 2016. Ray. Ajit. Kambali. Maltesh. Ravindranath. Vijayalakshmi.
  2. 10.1021/acs.biochem.5b01132. Regulation of DJ-1 by glutaredoxin 1 in vivo – implications for Parkinson's disease. Biochemistry. 2016. Johnson. William M.. Golczak. Marcin. Choe. Kyonghwan. Curran. Pierce L.. Gorelenkova Miller. Olga. Yao. Chen. Wang. Wenzhang. Lin. Jiusheng. Milkovic. Nicole M.. Ray. Ajit. Ravindranath. Vijayalakshmi. Zhu. Xiongwei. Wilson. Mark A.. Wilson-Delfosse. Amy L.. Chen. Shu G.. Mieyal. John Joseph. 26894491. 4987251. 55. 32. 4519–32.
  3. 10.1038/nature16036. 26580328. Regional research priorities in brain and nervous system disorders. Nature. 527. 7578. S198–206. 2015. Ravindranath. Vijayalakshmi. Dang. Hoang-Minh. Goya. Rodolfo G.. Mansour. Hader. Nimgaonkar. Vishwajit L.. Russell. Vivienne Ann. Xin. Yu. 2015Natur.527S.198R . free. 11336/48799. free.
  4. 10.1016/j.freeradbiomed.2015.06.041. 26164633. MPTP activates ASK1–p38 MAPK signaling pathway through TNF-dependent Trx1 oxidation in parkinsonism mouse model. Free Radical Biology and Medicine. 87. 312–25. 2015. Ray. Ajit. Sehgal. Neha. Karunakaran. Smitha. Rangarajan. Govindan. Ravindranath. Vijayalakshmi.
  5. 10.1016/j.freeradbiomed.2014.06.004. 24933620. Critical cysteines in Akt1 regulate its activity and proteasomal degradation: Implications for neurodegenerative diseases. Free Radical Biology and Medicine. 74. 118–28. 2014. Ahmad. Faraz. Nidadavolu. Prakash. Durgadoss. Lalitha. Ravindranath. Vijayalakshmi.
  6. Book: 10.2217/fmeb2013.14.9. Occurrence, distribution and potential actions of CYP2D6 in the brain. CYP2D6: Genetics, Pharmacology and Clinical Relevance. 102–116. 2014. Ravindranath. Vijayalakshmi. 978-1-78084-462-6.
  7. 10.1517/17425255.2013.759208. 23330950. Cytochrome P450-mediated metabolism in brain: Functional roles and their implications. Expert Opinion on Drug Metabolism & Toxicology. 9. 5. 551–8. 2013. Ravindranath. Vijayalakshmi. Strobel. Henry W. 12723035.

Notes and References

  1. Web site: Prof. Vijayalakshmi Ravindranath. Indian Institute of Science. 6 October 2014. 12 October 2014. https://web.archive.org/web/20141012184154/http://www.cns.iisc.ernet.in/viji/. dead.
  2. Book: Ravindranath. Vijayalakshmi. Lilavathi Daughters. 11 October 2014.
  3. Web site: Centre for Brain Research. 11 October 2014. 15 August 2022. https://web.archive.org/web/20220815215028/https://www.cbr.iisc.ac.in/director/. dead.
  4. Web site: Awardee Details: Shanti Swarup Bhatnagar Prize . 2016-07-18 . https://web.archive.org/web/20160819000745/http://ssbprize.gov.in/content/Detail.aspx?AID=15 . 2016-08-19 . dead .
  5. Web site: Biographical Sketch of Dr. Vijayalakshmi Ravindranath . https://web.archive.org/web/20160816103634/http://www.iiscalumni.com/news-events/downloads/Photo%20&%20CV_Prof.Vijayalakshmi%20Ravindranath.pdf. dead. 2016-08-16. 2016-08-16. 2019-02-16.
  6. Web site: List of Fellows . National Academy of Medical Sciences . 2016 . 19 March 2016.
  7. Web site: Archived copy . 2016-07-18 . https://web.archive.org/web/20160816103634/http://www.iiscalumni.com/news-events/downloads/Photo%20%26%20CV_Prof.Vijayalakshmi%20Ravindranath.pdf . 2016-08-16 . dead .
  8. Web site: Career in CSIR. www.csir.res.in. 2015-08-09. https://web.archive.org/web/20120210163924/http://www.csir.res.in/External/Utilities/Frames/career/main_page.asp?a=topframe.htm&b=leftcon.htm&c=..%2F..%2F..%2FHeads%2Fcareer%2Fawards.htm. 2012-02-10. dead.
  9. Web site: Shri Om Prakash Bhasin Awards – Health and Medical Sciences. 16 July 2016. 18 February 2022. https://web.archive.org/web/20220218064129/http://www.opbfawards.com/health.html. dead.
  10. Web site: Indian Fellow, Dr V Ravindranath. Indian National Science Academy. 6 October 2014.

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