Sinecatechins Explained

Sinecatechins (USAN, trade names Veregen and Polyphenon E) is a specific water extract of green tea leaves from Camellia sinensis that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts.[1] [2] [3] Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate.[4] It was the first botanical drug approved by the US FDA.

Notes and References

  1. Web site: Veregen label information. 2015-05-02.
  2. Masters KP . 2009 . New Drug Reviews: Sinecatechins (Veregen) for External Genital and Perianal Warts . Am Fam Physician . 80 . 12. 1447–1454 .
  3. Fürst R, Zündorf I . 2014. Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress . Mediators Inflamm . 2014 . 146832 . 10.1155/2014/146832 . 24987194 . 4060065 . free.
  4. Mayeaux EJ, Dunton C . Modern management of external genital warts . J Low Genit Tract Dis . 12 . 3 . 185–192. July 2008 . 18596459 . 10.1097/LGT.0b013e31815dd4b4 . 33302840 .

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