| Velká Jesenice | |
| Settlement Type: | Municipality |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name1: | Hradec Králové |
| Subdivision Type2: | District |
| Subdivision Name2: | Náchod |
| Pushpin Map: | Czech Republic |
| Pushpin Relief: | 1 |
| Pushpin Map Caption: | Location in the Czech Republic |
| Coordinates: | 50.3611°N 16.0378°W |
| Established Title: | First mentioned |
| Established Date: | 1436 |
| Area Total Km2: | 14.72 |
| Elevation M: | 286 |
| Population As Of: | 2024-01-01 |
| Population Footnotes: | [1] |
| Population Total: | 748 |
| Population Density Km2: | auto |
| Timezone1: | CET |
| Utc Offset1: | +1 |
| Timezone1 Dst: | CEST |
| Utc Offset1 Dst: | +2 |
| Postal Code Type: | Postal codes |
| Postal Code: | 551 01, 552 24 |
Velká Jesenice (German: Groß Jessenitz) is a municipality and village in Náchod District in the Hradec Králové Region of the Czech Republic. It has about 700 inhabitants.
The villages of Veselice and Volovka are administrative parts of Velká Jesenice.