| Official Name: | Velika Popina |
| Native Name: | [1] |
| Settlement Type: | Village |
| Pushpin Map: | Croatia |
| Pushpin Label Position: | bottom |
| Coordinates: | 44.2878°N 16.0325°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Croatia |
| Subdivision Type1: | Region |
| Subdivision Type2: | County |
| Subdivision Name2: | Zadar |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Gračac |
| Unit Pref: | Imperial |
| Area Footnotes: | [2] |
| Area Total Km2: | 50.2 |
| Population As Of: | 2021 |
| Population Total: | 42 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Timezone Dst: | CEST |
| Utc Offset: | +1 |
| Utc Offset Dst: | +2 |
| Postal Code: | 23442 Otrić |
Velika Popina (Serbian: Велика Попина) is a village in Croatia. The settlement is administered as a part of Gračac municipality, Zadar County.
According to national census of 2011, population of the settlement is 71. The majority of the population are Serbs.[3] [4] This represents 20.17% of its pre-war population according to the 1991 census.
The 1991 census[5] recorded that 95.17% of the village population were ethnic Serbs (335/352), 0.28% were Yugoslavs (1/352) while 4.54% were unknown (16/352).