| Official Name: | Velika Braina |
| Native Name: | Велика Браина |
| Settlement Type: | Village |
| Pushpin Map: | Serbia |
| Pushpin Label Position: | right |
| Subdivision Type: | Country |
| Subdivision Name: |  Serbia |
| Subdivision Type1: | Region |
| Subdivision Name1: | Southern and Eastern Serbia |
| Subdivision Type2: | District |
| Subdivision Name2: | Jablanica |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Medveđa |
| Unit Pref: | Metric |
| Area Footnotes: | [1] |
| Area Total Km2: | 11.50 |
| Population As Of: | 2011 |
| Population Total: | 28 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Coordinates: | 42.7989°N 21.4136°W |
| Elevation M: | 781 |
Velika Braina is a village located in the municipality of Medveđa, Serbia. According to the 2011 census, the village has a population of 28 inhabitants.[2]
| 1948 | 1953 | 1961 | 1971 | 1981 | 1991 | 2002 | 2011 | |
| 289 | 291 | 231 | 125 | 84 | 59 | 21 | 28 |