Vectorial synthesis is synthesis of exported proteins by ribosomes in which the ribosome-nascent chain complex is bound directly to the endoplasmic reticulum (ER) and the nascent peptide chain moves through the ER membrane as it emerges from the ribosome.[1]
Fuller-Pace, F., Peters, G., Dickson, C. Cell transformation by kFGF requires secretion but not glycosylation, Journal of Cell Biology (1991) 115 (2), pp. 547–555