| Varennes-le-Grand | |
| Commune Status: | Commune |
| Insee: | 71555 |
| Postal Code: | 71240 |
| Arrondissement: | Chalon-sur-Saône |
| Canton: | Saint-Rémy |
| Mayor: | Éric Valentim[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Le Grand Chalon |
| Coordinates: | 46.7122°N 4.8781°W |
| Elevation M: | 190 |
| Elevation Min M: | 172 |
| Elevation Max M: | 206 |
| Area Km2: | 19.08 |
Varennes-le-Grand (in French pronounced as /vaʁɛn lə ɡʁɑ̃/) is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.
The Grosne forms most of the commune's southeastern border. The Saône forms the commune's northeastern border.