Vallelunga (South Tyrol) Explained

Vallelunga (it|Vallelunga, de|Langtaufers) is a valley in South Tyrol, Italy. It is a side valley of the Venosta Valley.^[1] There is a small village in the valley, also named Vallelunga. In 2002-2003 it had an adult population of 339.^[2]

Vallelunga, along with two other villages in the Venosta Valley, Stelvio and Martello, were chosen as the subject of a genetic study begun in 2002. They were chosen because they had small populations that had been isolated for centuries. The investigators believed that such populations could shed light on the etiology of diseases.^[2] The data from this study has been used in a number of research papers.^{[3] [4] [5] [6]}

References

46.837°N 10.634°W

Notes and References

1. Enrico Massetti, "Reschenpass – Resia Pass", Südtirol and Dolomites, Enrico Massetti Publishing, 2018 .
2. Cristian Pattaro, Fabio Marroni, Alice Riegler, Deborah Mascalzoni, Irene Pichler, Claudia B Volpato, Umberta Dal Cero, Alessandro De Grandi, Clemens Egger, Agatha Eisendle, Christian Fuchsberger, Martin Gögele, Sara Pedrotti, Gerd K Pinggera, Stefan A Stefanov, Florian D Vogl, Christian J Wiedermann, Thomas Meitinger, Peter P Pramstaller, "The genetic study of three population microisolates in South Tyrol (MICROS): study design and epidemiological perspectives", BMC Medical Genetics, vol. 8, p. 29-43, 2007
3. F. Marroni, D. Grazio, C. Pattaro, M. Devoto, P. Pramstaller, "Estimates of genetic and environmental contribution to 45 quantitative traits support sharing of a homogeneous environment in an isolated population from South Tyrol, Italy", Human Heridity, vol. 65, no. 3, pp. 175-182, 2008.
4. Ghazal Zaboli, Adam Ameur, Wilmar Igl, Åsa Johansson, Caroline Hayward, Veronique Vitart, Susan Campbell, Lina Zgaga, Ozren Polasek, Gerd Schmitz, Cornelia van Duijn, Ben Oostra, Peter Pramstaller, Andrew Hicks, Tomas Meitinger, Igor Rudan, Alan Wright, James F Wilson, Harry Campbell, Ulf Gyllensten, "Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits", European Journal of Human Genetics, vol. 20, pp. 77-83, 2012.
5. Ginevra Biino, Paolo Gasparini, Pio D’Adamo, Marina Ciullo, Teresa Nutile, Daniela Toniolo, Cinzia Sala, Cosetta Minelli, Martin Gögele, Carlo L. Balduini, "Influence of age, sex and ethnicity on platelet count in five Italian geographic isolates: mild thrombocytopenia may be physiological", British Journal of Haematology, vol. 157, iss. 3, pp. 384-387, May 2012.
6. Wilmar Igl, Åsa Johansson, James F. Wilson, Sarah H. Wild, Ozren Polašek, Caroline Hayward, Veronique Vitart, Nicholas Hastie, Pavao Rudan, Carsten Gnewuch, Gerd Schmitz, Thomas Meitinger, Peter P. Pramstaller, Andrew A. Hicks, Ben A. Oostra, Cornelia M. van Duijn, Igor Rudan, Alan Wright, Harry Campbell, Ulf Gyllensten, "Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels", PLOS Genetics, vol. 6, iss. 1, January 2010.