| Valle-di-Mezzana | |
| Commune Status: | Commune |
| Arrondissement: | Ajaccio |
| Canton: | Gravona-Prunelli |
| Insee: | 2A336 |
| Postal Code: | 20167 |
| Mayor: | Horace Franchi[1] |
| Term: | 2021 - 2026 |
| Intercommunality: | CA Pays Ajaccien |
| Coordinates: | 42.0264°N 8.8256°W |
| Elevation M: | 400 |
| Elevation Min M: | 174 |
| Elevation Max M: | 827 |
| Area Km2: | 6.99 |
Valle-di-Mezzana is a commune in the Corse-du-Sud department of France on the island of Corsica.