Valentín Fuster Explained

Honorific-Prefix:The Most Excellent
The Marquess of Fuster
Honorific-Suffix:GCA
Birth Date:20 January 1943
Birth Place:Barcelona, Spain
Alma Mater:University of Barcelona
University of Edinburgh Medical School
Nationality:Spanish, American[1] [2] [3] [4]
Occupation:Cardiologist
Parents:Joaquín Fuster, Father
Relatives:Marquess of Carulla, grandmother
Joaquín Fuster, brother
Birthname:Valentín Fuster Carulla

Valentín Fuster Carulla, 1st Marquess of Fuster (born January 20, 1943) is a Spanish cardiologist and aristocrat.[5] [2] [3] [4]

He is editor-in-chief of the Journal of the American College of Cardiology (JACC),[6] past President of the American Heart Association,[7] past President of the World Heart Federation,[7] and has been a member of the US National Academy of Medicine[7] and Member of the European Horizon 2020 Scientific Panel of Health.[8] In 2016 he co-chaired, with Jendayi Frazer, the Advisory Committee on The Role of the United States on Global Health.[9]

Fuster serves as President of Mount Sinai Heart[10] [11] and Physician-in-Chief of The Mount Sinai Hospital, and Director of the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Richard Gorlin, MD/Heart Research Foundation, and Professor at Icahn School of Medicine at Mount Sinai.[12] In October 2023 Mount Sinai Heart was renamed the Mount Sinai Fuster Heart Hospital.[13] Deepak Bhatt succeeded Fuster in the role of director.[14]

He serves in Madrid as the General Director of the National Centre for Cardiovascular Research (CNIC)[15] and also chairs an international project, the SHE Foundation (Science for Health and Education). In 2014, King Juan Carlos I of Spain granted him the title of Marquis for his "outstanding and unceasing research efforts and his educational outreach work".[16]

Life and career

Fuster was born in Barcelona, Spain. He is the son of a psychiatrist, and his brother is a neuroscientist.[17] In Spain he competed in tennis at a national level.[18] Pedro Farreras Valentí, the author of the widely used Spanish textbook Farreras-Rozman Internal Medicine,[19] encouraged Fuster to study cardiology.[20]

Fuster graduated first in his class with an MD from University of Barcelona in 1967.[21] He completed an internship at the Hospital Clinic in Barcelona, then attended University of Edinburgh Medical School for a PhD on the role of platelets in myocardial infarction.[22]

Fuster served as a Research Fellow in Cardiology at the Royal Infirmary of Edinburgh from 1968 to 1971[22] After completing his PhD in 1971 from the University of Edinburgh Medical School. Fuster spent several years at the Mayo Clinic, first as a resident and later as Professor of Medicine and Consultant in Cardiology. In 1981, he became head of cardiology at Mount Sinai School of Medicine. From 1991 to 1994, he was Mallinckrodt Professor of Medicine at Harvard Medical School and Chief of Cardiology at the Massachusetts General Hospital.[23] He returned to Mount Sinai in 1994 as Director of the Zena and Michael A. Wiener Cardiovascular Institute and in 2006 named the Director of Mount Sinai Heart, and in 2022, he was appointed president.

Fuster serves as physician-in-chief and President of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josee and Henry R. Kravis Center for Cardiovascular Health. He is also the Richard Gorlin, MD/Heart Research Foundation Professor at Icahn School of Medicine at Mount Sinai.[12] Fuster was the President of Science,[24] and is now the General Director of the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) in Madrid, (Spain).[25]

Fuster was elected editor-in-chief at the Journal of the American College of Cardiology in 2014.[26] Former positions include President of the American Heart Association,[27] past president of the World Heart Federation,[28] member of the Institute of Medicine of the National Academy of Sciences[29] where he serves as Chair of the Committee on Preventing the Global Epidemic of Cardiovascular Disease,[30] former member of the National Heart, Lung, and Blood Institute Advisory Council,[31] and former Chairman of the Fellowship Training Directors Program of the American College of Cardiology. He has thirty-four university Honorary Doctorates.[12] [25] According to Google Scholar, his peer-reviewed publications, as of 2020, have been cited 319,356. His h-index is 209 and i10-index is 1,206.[32]

He was the inspiration for a character on the Spanish version of Sesame Street named "Valentin Ruster" that educated children in healthier lifestyles through exercise and healthy diet.[33]

Honors and awards

Scientific investigator

Chronology

Fuster’s contributions for disease-to-health transitions encompass five phases leading to 4 guidelines Class I:

1980s:  Demonstrating the role of platelets in coronary artery bypass graft (CABG) occlusion based on imaging studies in dogs, and a pioneering trial of aspirin in human atherothrombotic disease.[44] [45]

1990s:  Demonstrating that acute coronary events arise from small plaques, explaining their unpredictability,[46] and developing diagnostic MRI imaging to characterize these “vulnerable  plaques”[47] [48]  and inhibiting post coronary angioplasty (PCI) fibrosis in pigs by Rapamycin,[48] [49] prompting the introduction of drug-eluting stents (DES) to prevent PCI restenosis.[50]

2000s:  Following upon experience with CABG and DES for revascularization in patients with diabetes and multivessel coronary disease changing American and European practice guidelines.[51]

2010s:  To improve poor medication adherence, as observed in FREEDOM and other studies, a fixed-dose polypill (aspirin, ramipril and statin) was developed, the first approved for secondary prevention in 40 countries.[52]

2015 to present (2021): Established the predictive value of identifying atherosclerotic burden by noninvasive imaging (3D ultrasound, EBCT, PET, MRI) and genetics in 4 studies of 11,000 asymptomatic adults.[53] [54] [55] [56]  Thus, in collaboration with the producers of Sesame Street television, conducted randomized studies of 3,000 children, 2,000 parents and 300 teachers in Colombia, Spain and Harlem (New York). Sixty hours of health education over six months showed a significant impact on knowledge, attitude, habits and weight within three years.[57]

Books

Author

Editor

External links

Notes and References

  1. Web site: Dr Valentí Fuster . 20 August 2015.
  2. Web site: Valentin Fuster . 20 August 2015.
  3. Web site: Spain Honors Valentin Fuster, MD, PhD, of The Mount Sinai Medical Center . Mount Sinai . 25 Jul 2013 . 20 August 2015.
  4. Web site: Mellado, Ana . Valentín Fuster. el guardian de la salud de las estrellas . . 25 Jul 2013 . 20 August 2015.
  5. Web site: Dr Valentin Fuster . 20 August 2015.
  6. Web site: About Journal of the American College of Cardiology. 2020-11-12. www.jacc.org.
  7. Web site: American Heart Association To Honor Valentin Fuster, MD, PhD at Long Island Heart and Stroke Ball – American Heart Association – Eastern States. 2020-11-12. easternstates.heart.org.
  8. Web site: Register of Commission expert groups and other similar entities. 2021-08-25. ec.europa.eu.
  9. Web site: Prominent cardiologist Valentin Fuster to lead global health committee. 2021-08-25. www.cardiovascularbusiness.com. en.
  10. Web site: 2022-10-18 . Dr. Valentin Fuster l The Mount Sinai Hospital . 2022-12-02 . Crain's New York Business . en.
  11. Web site: Cardiologist Valentin Fuster named president of Mount Sinai Heart . 2022-12-02 . cardiovascularbusiness.com . en.
  12. http://www.mountsinai.org/profiles/valentin-fuster "Doctor Profile", Mount Sinai Hospital
  13. Web site: Mount Sinai renames leading heart hospital after cardiologist Valentin Fuster . 2024-03-11 . cardiovascularbusiness.com . en.
  14. Web site: Interventional cardiologist Deepak L. Bhatt, MD, named new director of Mount Sinai Heart . 2024-03-13 . cardiovascularbusiness.com . en.
  15. Centro Nacional de Investigaciones CardiovasculareWeb site: Fuster Carulla, Valentín . Centro Nacional de Investigaciones Cardiovasculares . 3 September 2021 . https://web.archive.org/web/20150923205027/https://www.cnic.es/en/personal/person.php?p=m_inv&per=415 . 23 September 2015 . dead.
  16. Web site: BOLETÍN OFICIAL DEL ESTADO. August 25, 2021. BOE. Spanish.
  17. Web site: 2014-06-30. 'El origen de la libertad está en la corteza cerebral'. 2020-10-28. ELMUNDO. es.
  18. O'Rourke. Robert. 2006. ValentÍn Fuster. Clinical Cardiology. 29. 12. 556–557. 10.1002/clc.20038. 17190182. 6654763.
  19. http://www.historiaveterinaria.org/update/5-1456756155.pdf Pedro Farreras (1876-1955).
  20. Web site: Las ocho claves para vivir mejor. 2020-10-28. BBVA Aprendemos juntos. es-ES.
  21. 2000-07-01. Valentin Fuster, MD, PhD: a conversation with the editor1. American Journal of Cardiology. en. 86. 2. 182–197. 10.1016/S0002-9149(00)00940-1. 0002-9149. 10913480. Fuster. V..
  22. Web site: VALENTIN FUSTER, M.D., PH.D. Curriculum Vitae. Mount Sinai. 17 August 2013.
  23. O'Rourke. R. A.. 2006. Valentin Fuster. Clinical Cardiology. 29. 12. 556–557. 10.1002/clc.20038. 6654763. 17190182.
  24. Web site: About the CNIC. November 12, 2020. Spanish National Center for Cardiovascular Health.
  25. http://www.cnic.es/en/personal/person.php?p=m_inv&per=415 "Valentin Fuster Carulla", CNIC
  26. Web site: Editor-in-Chief Biography . Journal of the American College of Cardiology . 3 September 2021.
  27. Fuster. Valentin. 2006 . Passing the Torch . Journal of the American Heart Association. 100. 2. 106. 10.1161/01.CIR.100.2.106 . 10402436. free.
  28. Web site: Biography - Past President . World Heart Federation . 3 September 2021 . https://web.archive.org/web/20160811100137/http://www.world-heart-federation.org/about-us/board/biographies/biography-past-president/ . 11 August 2016 . dead.
  29. Wood. Shelley . 2000 . Valentin Fuster Elected to Institute of Medicine . HeartWire .
  30. https://www.ncbi.nlm.nih.gov/books/NBK45687/ "Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries", CNIC
  31. http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3full.pdf "Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report", NHLBI
  32. Web site: Valentin Fuster. 2021-05-20. scholar.google.es.
  33. Web site: barrio sésamo: monstruos supersanos . Sesame Workshop . 3 September 2021 . https://web.archive.org/web/20181229064113/http://www.sesameworkshop.org/press-room/barrio-sesamo-monstruos-supersanos/ . 29 December 2018 . dead.
  34. http://www.theheart.org/article/1236589/print.do "Valentin Fuster Honored with Grand Prix Award", TheHeart
  35. http://my.americanheart.org/professional/Councils/DistinguishedScientists/Previous-Years-Distinguished-Scientists_UCM_321415_SubHomePage.jsp "Previous Years Distinguished Scientists", American Heart Association
  36. http://www.fpa.es/en/1996-valentin-fuster-carulla.html?texto=trayectoria&especifica=0 "Valentin Fuster - Technical & Scientific Research 1996", Fundacion Principe de Asturias
  37. http://my.americanheart.org/professional/Councils/AwardsandLectures/CareerAchievement/James-B-Herrick-Award-for-Outstanding-Achievement-in-Clinical-Cardiology_UCM_322613_Article.jsp "James B. Herrick Award for Outstanding Achievement in Clinical Cardiology", American Heart Association
  38. http://www.newswise.com/articles/iasc-presents-dr-valentin-fuster-with-the-distinguished-researcher-award "IASC Presents Valentin Fuster with the Distinguished Researcher Award", Newswise
  39. http://www.cnic.es/en/personal/person.php?p=m_inv&per=415 "Valentin Fuster Biography", CNIC
  40. News: Valentin Fuster. 2015-04-21. Institut de France. Grands Prix des Fondations. 2017-12-12.
  41. http://newsroom.heart.org/news/new-york-city-scientist-wins-american-240295 "New York City scientist wins American Heart Association award for major additions to knowledge of artery disease process, treatments", American Heart Association
  42. https://www.boe.es/buscar/doc.php?id=BOE-A-2017-12699 Royal Decree 967/2017, 3rd november
  43. Web site: Announcement of the Prince Mahidol Award 2020 Laureates. 2020-11-12. thailand.prd.go.th.
  44. Fuster. V.. Dewanjee. M. K.. Kaye. M. P.. Josa. M.. Metke. M. P.. Chesebro. J. H.. Noninvasive radioisotopic technique for detection of platelet deposition in coronary artery bypass grafts in dogs and its reduction with platelet inhibitors. Circulation. 1979. 60. 7. 1508–1512. 10.1161/01.cir.60.7.1508. 0009-7322. 315282. 961157. free.
  45. Chesebro. J. H.. Fuster. V.. Elveback. L. R.. Clements. I. P.. Smith. H. C.. Holmes. D. R.. Bardsley. W. T.. Pluth. J. R.. Wallace. R. B.. Puga. F. J.. 1984-01-26. Effect of dipyridamole and aspirin on late vein-graft patency after coronary bypass operations. The New England Journal of Medicine. 310. 4. 209–214. 10.1056/NEJM198401263100401. 0028-4793. 6361561.
  46. Ambrose. J. A.. Tannenbaum. M. A.. Alexopoulos. D.. Hjemdahl-Monsen. C. E.. Leavy. J.. Weiss. M.. Borrico. S.. Gorlin. R.. Fuster. V.. Angiographic progression of coronary artery disease and the development of myocardial infarction. Journal of the American College of Cardiology. 1988. 12. 1. 56–62. 10.1016/0735-1097(88)90356-7. 0735-1097. 3379219. 9009129 . free.
  47. Fuster. Valentin. Badimon. Lina. Badimon. Juan J.. Chesebro. James H.. 1992-01-30. The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes. New England Journal of Medicine. 326. 5. 310–318. 10.1056/NEJM199201303260506. 0028-4793. 1728735.
  48. Fuster. V.. Fayad. Z. A.. Badimon. J. J.. Acute coronary syndromes: biology. Lancet. 1999. 353. Suppl 2 . SII5–9. 10.1016/s0140-6736(99)90234-9. 0140-6736. 10374759. 34043897.
  49. Poon. Michael. Badimon. Juan Jose. Fuster. Valentin. 2002. Viewpoint Overcoming restenosis with sirolimus: From alphabet soup to clinical reality. The Lancet. 359. 9306. 619–622. 10.1016/S0140-6736(02)07751-6. 11867133. 41817456.
  50. Poon. Michael. Badimon. Juan Jose. Fuster. Valentin. 2002-02-16. Overcoming restenosis with sirolimus: from alphabet soup to clinical reality. Lancet. 359. 9306. 619–622. 10.1016/s0140-6736(02)07751-6. 0140-6736. 11867133. 41817456.
  51. Farkouh. Michael E.. Domanski. Michael. Sleeper. Lynn A.. Siami. Flora S.. Dangas. George. Mack. Michael. Yang. May. Cohen. David J.. Rosenberg. Yves. Solomon. Scott D.. Desai. Akshay S.. 2012-12-20. Strategies for multivessel revascularization in patients with diabetes. The New England Journal of Medicine. 367. 25. 2375–2384. 10.1056/NEJMoa1211585. 1533-4406. 23121323. 2065089 . free.
  52. Castellano. José M.. Sanz. Ginés. Peñalvo. José L.. Bansilal. Sameer. Fernández-Ortiz. Antonio. Alvarez. Luz. Guzmán. Luis. Linares. Juan Carlos. García. Fernando. D'Aniello. Fabiana. Arnáiz. Joan Albert. A polypill strategy to improve adherence: results from the FOCUS project. Journal of the American College of Cardiology. 2014. 64. 20. 2071–2082. 10.1016/j.jacc.2014.08.021. 1558-3597. 25193393. free.
  53. López-Melgar. Beatriz. Fernández-Friera. Leticia. Oliva. Belén. García-Ruiz. José Manuel. Peñalvo. José Luis. Gómez-Talavera. Sandra. Sánchez-González. Javier. Mendiguren. José María. Ibáñez. Borja. Fernández-Ortiz. Antonio. Sanz. Javier. 2017-07-18. Subclinical Atherosclerosis Burden by 3D Ultrasound in Mid-Life: The PESA Study. Journal of the American College of Cardiology. 70. 3. 301–313. 10.1016/j.jacc.2017.05.033. 1558-3597. 28705310. 205592222 . free. 20.500.12105/8353. free.
  54. Fernández-Friera. Leticia. Fuster. Valentín. López-Melgar. Beatriz. Oliva. Belén. Sánchez-González. Javier. Macías. Angel. Pérez-Asenjo. Braulio. Zamudio. Daniel. Alonso-Farto. Juan C.. España. Samuel. Mendiguren. José. 2019-04-02. Vascular Inflammation in Subclinical Atherosclerosis Detected by Hybrid PET/MRI. Journal of the American College of Cardiology. 73. 12. 1371–1382. 10.1016/j.jacc.2018.12.075. 1558-3597. 30922468. 85565316.
  55. Fernández-Friera. Leticia. Peñalvo. José L.. Fernández-Ortiz. Antonio. Ibañez. Borja. López-Melgar. Beatriz. Laclaustra. Martín. Oliva. Belén. Mocoroa. Agustín. Mendiguren. José. Martínez de Vega. Vicente. García. Laura. 2015-06-16. Prevalence, Vascular Distribution, and Multiterritorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort: The PESA (Progression of Early Subclinical Atherosclerosis) Study. Circulation. 131. 24. 2104–2113. 10.1161/CIRCULATIONAHA.114.014310. 1524-4539. 25882487. 20.500.12105/8352 . 469595. free.
  56. Jaiswal. Siddhartha. Natarajan. Pradeep. Silver. Alexander J.. Gibson. Christopher J.. Bick. Alexander G.. Shvartz. Eugenia. McConkey. Marie. Gupta. Namrata. Gabriel. Stacey. Ardissino. Diego. Baber. Usman. 2017-07-13. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease. The New England Journal of Medicine. 377. 2. 111–121. 10.1056/NEJMoa1701719. 1533-4406. 6717509. 28636844.
  57. Peñalvo. José L.. Santos-Beneit. Gloria. Sotos-Prieto. Mercedes. Bodega. Patricia. Oliva. Belén. Orrit. Xavier. Rodríguez. Carla. Fernández-Alvira. Juan Miguel. Redondo. Juliana. Vedanthan. Rajesh. Bansilal. Sameer. 2015-10-06. The SII Program for Cardiovascular Health Promotion in Early Childhood: A Cluster-Randomized Trial. Journal of the American College of Cardiology. 66. 14. 1525–1534. 10.1016/j.jacc.2015.08.014. 1558-3597. 26429075. 29173747 . free.

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