VTI1A explained
Vesicle transport through interaction with t-SNAREs homolog 1A is a protein that in humans is encoded by the VTI1A gene.[1] [2]
The protein encoded by the VTI1A gene is a vesicular-SNARE (v-SNARE) protein which is located in the membranes of target vesicle compartments.[3]
Further reading
- Luke MM, O'Meara ES, Rowland CM, etal . Gene Variants Associated With Ischemic Stroke: The Cardiovascular Health Study . Stroke . 40 . 2 . 363–8 . 2009 . 19023099 . 2881155 . 10.1161/STROKEAHA.108.521328 .
- Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 528928 . 10.1101/gr.2596504 .
- Grupe A, Li Y, Rowland C, etal . A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease . Am. J. Hum. Genet. . 78 . 1 . 78–88 . 2006 . 16385451 . 1380225 . 10.1086/498851 .
- Mallard F, Tang BL, Galli T, etal . Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform . J. Cell Biol. . 156 . 4 . 653–64 . 2002 . 11839770 . 2174079 . 10.1083/jcb.200110081 .
- Shiffman D, O'Meara ES, Bare LA, etal . Association of Gene Variants with Incident Myocardial Infarction in the Cardiovascular Health Study . Arterioscler. Thromb. Vasc. Biol. . 28 . 1 . 173–9 . 2008 . 17975119 . 2636623 . 10.1161/ATVBAHA.107.153981 .
- Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 1356129 . 10.1101/gr.4039406 .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 139241 . 10.1073/pnas.242603899 . 2002PNAS...9916899M . free .
- Flowerdew SE, Burgoyne RD . A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels . Biochem. J. . 418 . 3 . 529–40 . 2009 . 19138172 . 2650881 . 10.1042/BJ20081736 .
- Tai G, Lu L, Wang TL, etal . Participation of the Syntaxin 5/Ykt6/GS28/GS15 SNARE Complex in Transport from the Early/Recycling Endosome to the Trans-Golgi Network . Mol. Biol. Cell . 15 . 9 . 4011–22 . 2004 . 15215310 . 515336 . 10.1091/mbc.E03-12-0876 .
- Antonin W, Holroyd C, Fasshauer D, etal . A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function . EMBO J. . 19 . 23 . 6453–64 . 2000 . 11101518 . 305878 . 10.1093/emboj/19.23.6453 .
Notes and References
- Web site: Entrez Gene: vesicle transport through interaction with t-SNAREs homolog 1A (yeast).
- Fischer von Mollard G, Stevens TH . A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways . J. Biol. Chem. . 273 . 5 . 2624–30 . January 1998 . 9446565 . 10.1074/jbc.273.5.2624. free .
- Web site: VTI1A vesicle transport through interaction with t-SNAREs 1A [Homo sapiens (Human)] - Gene - NCBI.