L-tryptophan—pyruvate aminotransferase explained

L-tryptophan---pyruvate aminotransferase
Ec Number:2.6.1.99

L-tryptophan—pyruvate aminotransferase (TAA1 (gene), vt2 (gene)) is an enzyme with systematic name L-tryptophan:pyruvate aminotransferase.[1] [2] [3] [4] This enzyme catalyses the following chemical reaction

\rightleftharpoons

indole-3-pyruvate + L-alanine

This plant enzyme, along with EC 1.14.13.168, indole-3-pyruvate monooxygenase, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.

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Notes and References

  1. Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballaré CL, Sandberg G, Noel JP, Chory J . Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants . Cell . 133 . 1 . 164–76 . April 2008 . 18394996 . 2442466 . 10.1016/j.cell.2008.01.049 .
  2. Mashiguchi . K. . Tanaka . K. . Sakai . T. . Sugawara . S. . Kawaide . H. . Natsume . M. . Hanada . A. . Yaeno . T. . Shirasu . K. . Yao . H. . McSteen . P. . Paula McSteen. Zhao . Y. . Hayashi . K.-i. . Kamiya . Y. . Kasahara . H. . The main auxin biosynthesis pathway in Arabidopsis . Proceedings of the National Academy of Sciences . 8 November 2011 . 108 . 45 . 18512–18517 . 10.1073/pnas.1108434108. 22025724 . 3215075 . 2011PNAS..10818512M . free .
  3. Phillips KA, Skirpan AL, Liu X, Christensen A, Slewinski TL, Hudson C, Barazesh S, Cohen JD, Malcomber S, McSteen P . vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize . The Plant Cell . 23 . 2 . 550–66 . February 2011 . 21335375 . 3077783 . 10.1105/tpc.110.075267 .
  4. Zhao Y . Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants . Molecular Plant . 5 . 2 . 334–8 . March 2012 . 22155950 . 3309920 . 10.1093/mp/ssr104 .