VAMP5 explained

vesicle-associated membrane protein 5 (myobrevin)
Hgncid:12646
Symbol:VAMP5
Entrezgene:10791
Omim:607029
Refseq:NM_006634
Uniprot:O95183
Chromosome:2
Arm:p
Band:11.2

Vesicle-associated membrane protein 5 (VAMP-5) is a synaptobrevin protein encoded in the human by the VAMP5 gene.[1] [2]

Function

VAMPs (synaptobrevins) along with syntaxins and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.[2]

Notes and References

  1. Zeng Q, Subramaniam VN, Wong SH, Tang BL, Parton RG, Rea S, James DE, Hong W . A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane . Molecular Biology of the Cell . 9 . 9 . 2423–37 . September 1998 . 9725904 . 25509 . 10.1091/mbc.9.9.2423.
  2. Web site: Entrez Gene: STX12 syntaxin 12.