V-cath endopeptidase explained

V-cath endopeptidase
Ec Number:	3.4.22.50
Cas Number:	316365-69-2

V-cath endopeptidase (AcNPV protease, BmNPV protease, NPV protease, baculovirus cathepsin, nucleopolyhedrosis virus protease, viral cathepsin) is an enzyme.^{[1] [2]} This enzyme catalyses the following chemical reaction

Endopeptidase of broad specificity, hydrolyzing substrates of both cathepsin L and cathepsin B

This enzyme belongs to the peptidase family C1.

Notes and References

1. Slack JM, Kuzio J, Faulkner P . Characterization of v-cath, a cathepsin L-like proteinase expressed by the baculovirus Autographa californica multiple nuclear polyhedrosis virus . The Journal of General Virology . 76 (Pt 5) . 5 . 1091–8 . May 1995 . 7730794 . 10.1099/0022-1317-76-5-1091 . free .
2. Hawtin RE, Zarkowska T, Arnold K, Thomas CJ, Gooday GW, King LA, Kuzio JA, Possee RD . Liquefaction of Autographa californica nucleopolyhedrovirus-infected insects is dependent on the integrity of virus-encoded chitinase and cathepsin genes . Virology . 238 . 2 . 243–53 . November 1997 . 9400597 . 10.1006/viro.1997.8816 . free .