| Season: | 2006 |
| Competition: | Uzbek League |
| Winners: | Pakhtakor Tashkent |
| Relegated: | Sogdiana Jizzakh Xorazm FK Urganch |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Pakhtakor Neftchi Farg'ona |
| League Topscorer: | Pavel Solomin 21 goals |
| Prevseason: | 2005 |
| Nextseason: | 2007 |
The 2006 Uzbek League season was the 15th edition of top level football in Uzbekistan since independence from the Soviet Union in 1992.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Pavel Solomin | Traktor | 21 |
| 2 | Nosirbek Otakuziev | Neftchi | 19 |
| 3 |  Arif Mirzoýew | Navbahor | 18 |
| Server Djeparov | Pakhtakor | ||
| 5 | Bakhtiyor Hamidullaev | Andijan | 17 |
| Uche Iheruome | Pakhtakor | ||
| 7 | Kamoliddin Murzoev | Metallurg (8)/ Mash'al (7) | 15 |
| Nasaf | |||
| 9 | Zayniddin Tadjiyev | Pakhtakor | 14 |
| 10 | Igor Taran | Shurtan | 13 |
| Marsel Idiatullin | Lokomotiv | ||
| 12 | Zafar Kholmurodov | Mash'al (1)/ Nasaf (11) | 12 |
| 13 | Bakhrom Umarov | Metallurg | 11 |
| Rustam Kodirov | Mash'al | ||
| 15 | Pakhtakor | 10 | |
| Ilhom Mo'minjonov | Traktor | ||