| Season: | 2000 |
| Competition: | Uzbek League |
| Winners: | Do'stlik |
| League Topscorer: | Jafar Irismetov (45 goals) |
| Biggest Home Win: | Samarqand 8–0 Semurg A. |
| Biggest Away Win: | Sogdiana 1–8 Do'stlik |
| Highest Scoring: | Samarqand 6–3 Do'stlik Sogdiana 1–8 Do'stlik Sogdiana 3–6 Samarqand Navbahor 6–3 Sogdiana Semurg A. 4–5 Nasaf |
| Total Goals: | 1279 (3.37 per match) |
| Prevseason: | 1999 |
| Nextseason: | 2001 |
The 2000 Uzbek League season was the ninth edition of top level football in Uzbekistan since independence from the Soviet Union in 1992.
It was contested by 20 teams, and Do'stlik won the championship. Top scorer was Jafar Irismetov of Do'stlik with 45 goals, the most scored by one player in a single season.