| Season: | 1999 |
| Competition: | Uzbek League |
| Winners: | Do'stlik |
| Prevseason: | 1998 |
| Nextseason: | 2000 |
The 1999 Uzbek League season was the eighth edition of top-level football in Uzbekistan since independence from the Soviet Union in 1992.
It was contested by 16 teams, and Do'stlik won the championship.