| Birth Date: | 16 December 1987 |
| Birth Place: | Rüsselsheim, West Germany |
| Height: | [1] |
| Position: | Midfielder |
| Currentclub: | KSG Georgenhausen |
| Youthclubs1: | SG Astheim |
| Youthyears2: | –2009 |
| Youthclubs2: | SG Dornheim |
| Years1: | 2009–2014 |
| Clubs1: | SV Darmstadt 98 |
| Caps1: | 134 |
| Goals1: | 16 |
| Years2: | 2014–2018 |
| Clubs2: | Jahn Regensburg |
| Caps2: | 86 |
| Goals2: | 7 |
| Years3: | 2018–2019 |
| Clubs3: | Hessen Dreieich |
| Caps3: | 24 |
| Goals3: | 2 |
| Years4: | 2019–2020 |
| Caps4: | 15 |
| Goals4: | 1 |
| Years5: | 2020– |
| Clubs5: | KSG Georgenhausen |
| Caps5: | 8 |
| Goals5: | 1 |
| Club-Update: | 12:34, 30 January 2021 (UTC) |
| Manageryears1: | 2020– |
| Managerclubs1: | KSG Georgenhausen |
Uwe Hesse (born 16 December 1987) is a German footballer who plays for KSG Georgenhausen.[2]