| Uroš Desnica | |
| Birth Date: | 28 August 1874 |
| Birth Place: | Obrovac, Kingdom of Dalmatia, Austria-Hungary |
| Death Place: | Split, Governorate of Dalmatia, Kingdom of Italy |
| Alma Mater: | University of Vienna |
| Occupation: | Politician, lawyer |
Uroš Desnica (28 August 1874 – 1 July 1941) was a Croatian Serb and Yugoslavian politician and lawyer. He graduated law from the University of Vienna and practied law in Zadar until 1918. Desnica was a member of the Serb People's Party in the Kingdom of Dalmatia (then a part of Austria-Hungary). In 1905, he took part in the process of adoption of the — the decision of the Croatian Serb politicians in Dalmatia to endorse the . The latter was a political agreement between a number of Croatian and Croatian Serb political parties on an alliance which led to founding of the Croat-Serb Coalition. Following the end of the World War I and the dissolution of Austria-Hungary, Desnica was appointed the head of the regional Dalmatian government within the newly-established Kingdom of Serbs, Croats and Slovenes, and a member of the National Assembly elected on the People's Radical Party ticket. Upon introduction of the 6 January Dictatorship by the Alexander I of Yugoslavia, Desnica was appointed a senator by the king. In the interwar period, Desnica advocated the integral Yugoslavism, and joined the Chetnik movement in 1941.