Uracil glycol explained

Uracil glycol is a major oxidation product of cytosine in DNA. It can be readily bypassed by E. coli DNA polymerase I (unlike thymine glycol) and be a potent premutagenic lesion.^[1]

Notes and References

1. Web site: Enzymatic Processing of Uracil Glycol, a Major Oxidative Product of DNA Cytosine . Jbc.org . July 20, 2015.