Upinder Singh Bhalla Explained
Upinder Singh Bhalla |
Birth Date: | 1963 6, df=y |
Nationality: | Indian |
Known For: | Computational and experimental studies on neuronal and Synaptic signalling |
Upinder Singh Bhalla (born 1963) is an Indian computational neuroscientist, academic and a professor at National Centre for Biological Sciences of the Tata Institute of Fundamental Research.[1] He is known for his studies on neuronal and synaptic signalling in memory and olfactory coding using computational and experimental methods[2] and is an elected fellow of the Indian Academy of Sciences[3] and the Indian National Science Academy.[4] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences.[5] The Infosys Science Foundation[6] awarded him the Infosys Prize 2017 in Life Sciences for his pioneering contributions to the understanding of the brain's computational machinery.[7]
Biography
Upinder S. Bhalla, born in the Indian capital of Delhi to an academic couple who were professors at Jawaharlal Nehru University, enrolled himself at the Indian Institute of Technology, Kanpur for an integrated master's program but discontinued his studies at IITK after one year to join Cambridge University from where he graduated in natural sciences. Subsequently, he secured a PhD under the guidance of James M. Bower from California Institute of Technology in 1993 and did his post doctoral studies at the laboratory of Ravi Iyengar at Mount Sinai School of Medicine.[8] Returning to India, he joined National Centre for Biological Sciences, a Bengaluru-based biological research centre of Tata Institute of Fundamental Research where he became an assistant professor in 2002 and an associate professor in 2003, before becoming a professor in 2012.[9] He heads a laboratory at NCBS where he hosts a number of research associates, post-doctoral fellows and doctoral students who are involved in the research on Memory and Plasticity through computational and experimental methods.[10]
Legacy
Bhalla's research has widened our understanding of memory functioning and he has contributed to understanding the neural coding of olfactory information.[11] His team at NCBS uses optogenetic techniques for monitoring brain cell activity and uses light to stimulate the activity.[12] Bhalla and his colleagues developed MOOSE (Multiscale Object-Oriented Simulation Environment), a simulation tool which helps build computer models of molecules and molecular networks.[13] He has mentored several research scholars in their doctoral and post-doctoral studies[14] and is a member of the council of the Indian National Science Academy.[15]
Awards and honours
Bhalla received the Shanti Swarup Bhatnagar Prize of the Council of Scientific and Industrial Research in 2007 for his contributions to Biological Sciences. The same year, the Indian Academy of Sciences elected him as their fellow. Three years later, he also became an elected fellow of the Indian National Science Academy. In 2017, he received the Infosys Prize in Life Sciences for the excellent work he has been doing for the last two decades which is now not only nationally but internationally recognised as one of the fundamental ways of how we study the role of olfaction in behaviour.[16]
Selected bibliography
- Trafficking Motifs as the Basis for Two-Compartment Signaling Systems to Form Multiple Stable States . Upinder Singh Bhalla . Biophys. J. . July 2011 . 101 . 1 . 21–32 . 10.1016/j.bpj.2011.05.037. 3127183 . 21723811. 2011BpJ...101...21B .
- Robust and Rapid Air-Borne Odor Tracking without Casting . Bhattacharyya U, Bhalla US . eNeuro . December 2015 . 2 . 6 . ENEURO.0102–15.2015 . 10.1523/ENEURO.0102-15.2015. 4674010 . 26665165.
- NSDF: Neuroscience Simulation Data Format . Ray S, Chintaluri C, Bhalla US, Wójcik DK . Neuroinformatics . April 2016 . 14 . 2 . 147–67 . 10.1007/s12021-015-9282-5. 4823348 . 26585711.
- Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding . Gilra A, Bhalla US . PLOS ONE . May 2015 . 10 . 5 . 10.1371/journal.pone.0098045 . e0098045 . 25942312 . 4420273. 2015PLoSO..1098045G . free .
- Olfactory bulb coding of odors, mixtures and sniffs is a linear sum of odor time profiles . Gupta P, Albeanu DF, Bhalla US . Nat. Neurosci. . February 2015 . 18 . 2 . 272–81 . 10.1038/nn.3913. 25581362 . 205437247 .
- Transcription control pathways decode patterned synaptic inputs into diverse mRNA expression profiles . Jain P, Bhalla US . PLOS ONE . May 2014 . 9 . 5 . 10.1371/journal.pone.0095154 . e95154 . 24787753 . 4006808. 2014PLoSO...995154J . free .
- Molecular computation in neurons: a modeling perspective . Bhalla US . Curr Opin Neurobiol . April 2014 . 25 . 31–7 . 24709598 . 10.1016/j.conb.2013.11.006. 22243389 .
- CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning . Modi MN, Dhawale AK, Bhalla US . eLife . March 2014 . 3 . 10.7554/eLife.01982 . e01982. 3964823 . 24668171 . free .
- Multiscale modeling and synaptic plasticity . Bhalla US . Prog Mol Biol Transl Sci . Progress in Molecular Biology and Translational Science . 2014 . 123 . 351–86 . 10.1016/B978-0-12-397897-4.00012-7. 24560151 . 9780123978974 .
- Precise excitation-inhibition balance controls gain and timing in the hippocampus . Bhatia A, Moza S, Bhalla US. eLife . 2019 . 8 . 10.7554/eLife.43415 . 31021319 . 6517031. free.
See also
External links
Notes and References
- Web site: The Code Breaker: Upinder S. Bhalla . India Today . 10 September 2011 . 25 October 2016.
- Web site: Brief Profile of the Awardee . Shanti Swarup Bhatnagar Prize . 2016 . 5 October 2016.
- Web site: Fellow profile – Bhalla . Indian Academy of Sciences . 2016 . 6 October 2016.
- Web site: Indian fellow . Indian National Science Academy . 2016 . 25 October 2016.
- Web site: View Bhatnagar Awardees . Shanti Swarup Bhatnagar Prize . 2016 . 5 October 2016.
- Web site: Infosys Prize. infosys-science-foundation.com. 1 December 2017.
- Web site: Infosys Prize – Laureates 2017 – Prof. Upinder S. Bhalla. infosys-science-foundation.com. 1 December 2017.
- Web site: Upinder Singh Bhalla on Neurotree . Neurotree . 2016 . 25 October 2016.
- Web site: Upinder Singh Bhalla on Vidwan . Vidwan . 2016 . 25 October 2016.
- Web site: Lab members . National Centre For Biological Sciences . 2016 . 25 October 2016.
- Web site: Handbook of Shanti Swarup Bhatnagar Prize Winners . Council of Scientific and Industrial Research . 1999 . 5 October 2016 . 34.
- Web site: Computational and Experimental approaches to Memory and Plasticity . National Centre for Biological Sciences . 2016 . 25 October 2016.
- Web site: Contact US . Moose.ncbs . 2016 . 25 October 2016.
- Web site: Sachin Deshmukh . Wellcome Trust . 2016 . 25 October 2016.
- Web site: INSA Year Book 2016 . Indian National Science Academy . 2016 . 25 October 2016 . 11 of 337.
- Web site: Infosys Prize – Laureates 2017 – Prof. Upinder S. Bhalla. infosys-science-foundation.com. 1 December 2017.