| Election Name: | 1988 United States Senate election in Wisconsin |
| Country: | Wisconsin |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1982 United States Senate election in Wisconsin |
| Previous Year: | 1982 |
| Next Election: | 1994 United States Senate election in Wisconsin |
| Next Year: | 1994 |
| Election Date: | November 8, 1988 |
| Image1: | File:Sen Herb Kohl.jpg |
| Nominee1: | Herb Kohl |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 1,128,625 |
| Percentage1: | 52.08% |
| Nominee2: | Susan Engeleiter |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 1,030,440 |
| Percentage2: | 47.55% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | William Proxmire |
| Before Party: | Democratic Party (United States) |
| After Election: | Herb Kohl |
| After Party: | Democratic Party (United States) |
The 1988 United States Senate election in Wisconsin took place on November 8, 1988. Incumbent Democratic U.S. Senator William Proxmire decided to retire, instead of running for re-election to a sixth full term. Democrat Herb Kohl won the open seat.