| Election Name: | 1980 United States Senate election in New Hampshire |
| Country: | New Hampshire |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974–75 United States Senate elections in New Hampshire#Special election: September 1975 |
| Previous Year: | 1975 (special) |
| Next Election: | 1986 United States Senate election in New Hampshire |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | Warren Rudman.jpg |
| Nominee1: | Warren Rudman |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 195,559 |
| Percentage1: | 52.15% |
| Nominee2: | John Durkin |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 179,455 |
| Percentage2: | 47.85% |
| U.S. Senator | |
| Before Election: | John Durkin |
| Before Party: | Democratic Party (United States) |
| After Election: | Warren Rudman |
| After Party: | Republican Party (United States) |
The 1980 United States Senate election in New Hampshire was held on November 4, 1980. Incumbent Democratic U.S. Senator John Durkin was defeated by attorney Warren Rudman in a relatively close election, where nationwide Republicans would have a landslide election known as the Reagan Revolution.